Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …

Atherosclerotic cardiovascular disease is a major cause of death among humans. Animal
models have shown that cholesterol and inflammation are causatively involved in the …

Atherosclerosis is an inflammatory disease of the artery walls and involves immune cells
such as macrophages. Olfactory receptors (OLFRs) are G protein–coupled chemoreceptors …

People with kidney disease are disproportionately affected by atherosclerosis for unclear
reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived …

Atherosclerotic cardiovascular disease (CVD), the major cause of premature human
mortality, is a chronic and progressive metabolic and inflammatory disease in large-and …

Atherosclerosis is a maladaptive chronic inflammatory disease, which remains the leading
cause of death worldwide. The NLRP3 inflammasome constitutes a major driver of …

Background: Cholesterol loaded macrophage foam cells are a prominent feature of
atherosclerotic plaques. Single-cell RNA sequencing has identified foam cells as TREM2 …

Multiple types of renin-angiotensin system (RAS) blockers exist, allowing interference with
the system at the level of renin, angiotensin-converting enzyme, or the angiotensin II …

Current pharmacological treatments of atherosclerosis often target either cholesterol control
or inflammation management, to inhibit atherosclerotic progression, but cannot lead to direct …

Background: A significant burden of atherosclerotic disease is driven by inflammation.
Recently, microRNAs (miRNAs) have emerged as important factors driving and protecting …