Engineering interventions in industrial filamentous fungal cell factories for biomass valorization
A Madhavan, KB Arun, R Sindhu, AA Jose… - Bioresource …, 2022 - Elsevier
Filamentous fungi possess versatile capabilities for synthesizing a variety of valuable bio
compounds, including enzymes, organic acids and small molecule secondary metabolites …
compounds, including enzymes, organic acids and small molecule secondary metabolites …
Total Heterologous Biosynthesis of Fungal Natural Products in Aspergillus nidulans
Fungal natural products comprise a wide range of bioactive compounds including important
drugs and agrochemicals. Intriguingly, bioinformatic analyses of fungal genomes have …
drugs and agrochemicals. Intriguingly, bioinformatic analyses of fungal genomes have …
[HTML][HTML] Promoter regulation and genetic engineering strategies for enhanced cellulase expression in Trichoderma reesei
Background Trichoderma reesei has extraordinary potential for high-level protein production
at large scales, and it need to be further explored through genetic engineering tools to …
at large scales, and it need to be further explored through genetic engineering tools to …
[HTML][HTML] Evaluation of Aspergillus niger Six Constitutive Strong Promoters by Fluorescent-Auxotrophic Selection Coupled with Flow Cytometry: A Case for Citric Acid …
Y Lu, X Zheng, Y Wang, L Zhang, L Wang, Y Lei… - Journal of Fungi, 2022 - mdpi.com
Aspergillus niger is an important industrial workhorse for the biomanufacturing of organic
acids, proteins, etc. Well-controlled genetic regulatory elements, including promoters, are …
acids, proteins, etc. Well-controlled genetic regulatory elements, including promoters, are …
Plant‐associated endophytic fungi as potential bio‐factories for extracellular enzymes: Progress, Challenges and Strain improvement with precision approaches
D Raghav, A Jyoti, AJ Siddiqui… - Journal of Applied …, 2022 - academic.oup.com
There is an intricate network of relations between endophytic fungi and their hosts that
affects the production of various bioactive compounds. Plant‐associated endophytic fungi …
affects the production of various bioactive compounds. Plant‐associated endophytic fungi …
[HTML][HTML] Integrative transcriptome and proteome analyses of Trichoderma longibrachiatum LC and its cellulase hyper-producing mutants generated by heavy ion …
M Dong, S Wang, F Xu, G Xiao, J Bai, J Wang… - … for Biofuels and …, 2022 - Springer
Background The major challenge of facing the efficient utilization of biomass is the high cost
of cellulolytic enzyme, while the Trichoderma longibrachiatum plays an essential role in the …
of cellulolytic enzyme, while the Trichoderma longibrachiatum plays an essential role in the …
Homologous Expression and Characterization of α-L-rhamnosidase from Aspergillus niger for the Transformation of Flavonoids
H Ye, X Li, L Li, Y Zhang, J Zheng - Applied Biochemistry and …, 2022 - Springer
Aspergillus niger has been used for homologous and heterologous expressions of many
protein products. In this study, the α-L-rhamnosidase from A. niger (Rha-N1, GenBank …
protein products. In this study, the α-L-rhamnosidase from A. niger (Rha-N1, GenBank …
Construction of a novel filamentous fungal protein expression system based on redesigning of regulatory elements
Z Zhang, B Xiang, S Zhao, L Yang, Y Chen… - Applied Microbiology …, 2022 - Springer
Filamentous fungi are extensively used as an important expression host for the production of
a variety of essential industrial proteins. They have significant promise as an expression …
a variety of essential industrial proteins. They have significant promise as an expression …
Exploring a novel genomic safe-haven site in the human pathogenic mould Aspergillus fumigatus
Aspergillus fumigatus is the most important airborne fungal pathogen and allergen of
humans causing high morbidity and mortality worldwide. The factors that govern …
humans causing high morbidity and mortality worldwide. The factors that govern …
[HTML][HTML] A novel potent carrier for unconventional protein export in ustilago maydis
M Philipp, KP Hussnaetter, M Reindl… - Frontiers in Cell and …, 2022 - frontiersin.org
Recombinant proteins are ubiquitously applied in fields like research, pharma, diagnostics
or the chemical industry. To provide the full range of useful proteins, novel expression hosts …
or the chemical industry. To provide the full range of useful proteins, novel expression hosts …