Hurdle technology using encapsulated enzymes and essential oils to fight bacterial biofilms

S Mechmechani, S Khelissa, A Gharsallaoui… - Applied microbiology …, 2022 - Springer
Biofilm formation on abiotic surfaces has become a major public health concern because of
the serious problems they can cause in various fields. Biofilm cells are extremely resistant to …

Stress factors in protein drug product manufacturing and their impact on product quality

TK Das, A Sreedhara, JD Colandene, DK Chou… - Journal of …, 2022 - Elsevier
Injectable protein-based medicinal products (drug products, or DPs) must be produced by
using sterile manufacturing processes to ensure product safety. In DP manufacturing the …

The effect of different lyophilisation pressures on the microbiological stability, physicochemical, microstructural, and sensorial properties of yoghurt powders

Hİ Öztürk - International Dairy Journal, 2022 - Elsevier
This study investigated how different pressures used in the lyophilisation process affected
the physicochemical, microstructural, microbiological, and sensory properties of yoghurt …

Advances in nanocrystals as drug delivery systems

A Kaur, PK Parmar, S Jadhav, AK Bansal - Nanoparticle Therapeutics, 2022 - Elsevier
Poorly water-soluble drugs pose challenge of slow dissolution rate that can translate into
low bioavailability. Nanocrystals have been widely used for increasing apparent solubility …

Cytotoxicity and Thermal Characterization Assessment of Excipients for the Development of Innovative Lyophilized Formulations for Oncological Applications

F Susa, T Limongi, M Millone, V Cauda, R Pisano - Processes, 2022 - mdpi.com
Freeze-drying, also known as lyophilization, significantly improves the storage, stability,
shelf life, and clinical translation of biopharmaceuticals. On the downside, this process faces …