A roadmap to increase diversity in genomic studies

S Fatumo, T Chikowore, A Choudhury, M Ayub… - Nature medicine, 2022 - nature.com
Two decades ago, the sequence of the first human genome was published. Since then,
advances in genome technologies have resulted in whole-genome sequencing and …

Hypertension in the South African public healthcare system: a cost-of-illness and burden of disease study

CN Kohli-Lynch, A Erzse, BL Rayner, KJ Hofman - BMJ open, 2022 - bmjopen.bmj.com
Objectives To quantify the health and economic burden of hypertension in the South African
public healthcare system. Setting All inpatient, outpatient and rehabilitative care received in …

Early stage and established Hypertension in Sub-saharan Africa: results from Population Health surveys in 17 countries, 2010–2017

SS Shakil, D Ojji, CT Longenecker… - … Quality and Outcomes, 2022 - Am Heart Assoc
Background: Multiple studies have reported a high burden of hypertension in sub-Saharan
Africa, but none have examined early stage hypertension. We examined contemporary …

The meaning of health in rural South Africa: Gender, the life course, and the socioepidemiological context

SA Mojola, E Ice, E Schatz, N Angotti… - Population and …, 2022 - Wiley Online Library
This article examines the meaning of health among middle‐aged and older adults in a rural
South African setting, where 72 percent of adults aged 40 and over are living with a major …

Non-pharmacological interventions to achieve blood pressure control in African patients: a systematic review

M Cernota, ES Kroeber, T Demeke, T Frese… - BMJ open, 2022 - bmjopen.bmj.com
Objectives This systematic review aims to evaluate the evidence of non-pharmacological
strategies to improve blood pressure (BP) control in patients with hypertension from African …

A retrospective database study of the demographic features and glycemic control of patients with type 2 diabetes in Kinshasa, Democratic Republic of the Congo

D Sagastume, E Mertens, DK Sibongwere… - BMC medicine, 2022 - Springer
Abstract Background The Kin-Antwerp project aimed at improving the quality of care
provided to patients with diabetes in Kinshasa, the Democratic Republic of the Congo in …

[HTML][HTML] Sex and gender influence on cardiovascular health in sub-saharan Africa: findings from Ghana, Gambia, Mali, Guinea, and Botswana

R Dev, D Favour-Ofili, V Raparelli, H Behlouli… - Global Heart, 2022 - ncbi.nlm.nih.gov
Background: There is an upsurge of cardiovascular diseases (CVDs) in sub-Saharan Africa
(SSA). Irrespective of biological sex, gender-related factors could be the precursor of these …

Pancreatic ductal adenocarcinoma: Prognostic indicators of advanced disease

D Kruger, N Lahoud, YY Yako, J Devar, M Smith - PLoS One, 2022 - journals.plos.org
Background/Objectives Pancreatic ductal adenocarcinoma (PDAC) is an aggressive
malignancy associated with high metastatic risk. Prognosis remains poor even after …

Estimating the changing burden of disease attributable to high sodium intake in South Africa for 2000, 2006 and 2012

B Nojilana, N Abdelatif, A Cois, AE Schutte… - South African Medical …, 2022 - ajol.info
Background. Elevated sodium consumption is associated with increased blood pressure, a
major risk factor for cardiovascular and chronic kidney disease. Objectives. To quantify the …

Living kidney donation in a developing country

C Dayal, M Davies, NE Diana, A Meyers - PLoS One, 2022 - journals.plos.org
Background Living kidney donation has been advocated as a means to ameliorate the
chronic shortage of organs for transplantation. Significant rates of comorbidity and familial …