The biology of ependymomas and emerging novel therapies
Ependymomas are rare central nervous system tumours that can arise in the brain's
supratentorial region or posterior fossa, or in the spinal cord. In 1924, Percival Bailey …
supratentorial region or posterior fossa, or in the spinal cord. In 1924, Percival Bailey …
The oncogenic fusion landscape in pediatric CNS neoplasms
Pediatric neoplasms in the central nervous system (CNS) are the leading cause of cancer-
related deaths in children. Recent developments in molecular analyses have greatly …
related deaths in children. Recent developments in molecular analyses have greatly …
[HTML][HTML] Ependymomas
Ependymal neoplasms are a heterogenous group of neoplasms arising from the progenitors
of the cells lining the ventricular system and the spinal central canal. During the last few …
of the cells lining the ventricular system and the spinal central canal. During the last few …
Diffusely infiltrating glioma with CREBBP–BCORL1 fusion showing overexpression of not only BCORL1 but BCOR: A case report
A Yamazaki, Y Arai, K Fukuoka, Y Nakano… - Brain Tumor …, 2022 - Springer
BCORL1 encodes a transcriptional corepressor homolog to BCOR. BCORL1
rearrangements have been previously described as rare events, and among them, CREBBP …
rearrangements have been previously described as rare events, and among them, CREBBP …
Bevacizumab beyond progression for newly diagnosed glioblastoma (BIOMARK): phase II safety, efficacy and biomarker study
M Nagane, K Ichimura, R Onuki, D Narushima… - Cancers, 2022 - mdpi.com
Simple Summary This was a multicenter, single-arm, phase II study comprising two protocol
treatments. Patients were enrolled after craniotomy or biopsy and initiated the concurrent …
treatments. Patients were enrolled after craniotomy or biopsy and initiated the concurrent …
Molecular subgrouping of ependymoma across three anatomic sites and their prognostic implications
D Chinnam, K Gupta, T Kiran, A Saraswati… - Brain Tumor …, 2022 - Springer
The 2021 WHO classification stratifies ependymoma (EPN) into nine molecular subgroups
according to the anatomic locations which outperforms histological grading. We aimed at …
according to the anatomic locations which outperforms histological grading. We aimed at …
ZFTA (zinc finger translocation associated) fusion in supratentorial ependymomas: low prevalence in South Asians and no correlation with survival
A Goyal-Honavar, A Balasundaram, IP Thayakaran… - World Neurosurgery, 2022 - Elsevier
Background Supratentorial ependymomas (STEs) are an aggressive group of
ependymomas, topographically distinct from their posterior fossa and spinal counterparts …
ependymomas, topographically distinct from their posterior fossa and spinal counterparts …
[HTML][HTML] Pigmented ependymoma, a tumor with predilection for the middle-aged adult: case report with methylation classification and review of 16 literature cases
AS Himstead, M Perez-Rosendahl, GM Fote… - Free …, 2022 - ncbi.nlm.nih.gov
Ependymomas have rarely been described to contain pigment other than melanin,
neuromelanin, lipofuscin or a combination. In this case report, we present a pigmented …
neuromelanin, lipofuscin or a combination. In this case report, we present a pigmented …
[PDF][PDF] Mutation profiling of anaplastic ependymoma grade III by Ion
M Butt, S Alyami, T Nageeti, M Saeed, K AlQuthami… - academia.edu
Ependymomas are glial tumors derived from differentiated Background: ependymal cells. In
contrast to other types of brain tumors, histological grading is not a good prognostic marker …
contrast to other types of brain tumors, histological grading is not a good prognostic marker …