[HTML][HTML] Multifaceted functions of STING in human health and disease: from molecular mechanism to targeted strategy
Z Zhang, H Zhou, X Ouyang, Y Dong… - Signal transduction and …, 2022 - nature.com
Since the discovery of Stimulator of Interferon Genes (STING) as an important pivot for
cytosolic DNA sensation and interferon (IFN) induction, intensive efforts have been …
cytosolic DNA sensation and interferon (IFN) induction, intensive efforts have been …
[HTML][HTML] Regulation of IRF3 activation in human antiviral signaling pathways
MAL Hamrashdi, G Brady - Biochemical Pharmacology, 2022 - Elsevier
The interferon regulatory factor (IRF) family of transcription factors play a vital role in the
human innate antiviral immune responses with production of interferons (IFNs) as a hallmark …
human innate antiviral immune responses with production of interferons (IFNs) as a hallmark …
[HTML][HTML] Role of mitochondrial nucleic acid sensing pathways in health and patho-physiology
A Chowdhury, S Witte, A Aich - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Mitochondria, in symbiosis with the host cell, carry out a wide variety of functions from
generating energy, regulating the metabolic processes, cell death to inflammation. The most …
generating energy, regulating the metabolic processes, cell death to inflammation. The most …
[HTML][HTML] New insights into the crosstalk among the interferon and inflammatory signaling pathways in response to viral infections: defense or homeostasis
J Dai, P Zhou, S Li, HJ Qiu - Viruses, 2022 - mdpi.com
Innate immunity plays critical roles in eliminating viral infections, healing an injury, and
restoring tissue homeostasis. The signaling pathways of innate immunity, including …
restoring tissue homeostasis. The signaling pathways of innate immunity, including …
AKT2 reduces IFNβ1 production to modulate antiviral responses and systemic lupus erythematosus
X Zheng, J Xiao, Q Jiang, L Zheng, C Liu… - The EMBO …, 2022 - embopress.org
Abstract Interferon regulatory factor 3 (IRF3)‐induced type I interferon (I‐IFN) production
plays key roles in both antiviral and autoimmune responses. IRF3 phosphorylation …
plays key roles in both antiviral and autoimmune responses. IRF3 phosphorylation …
火炭母缓解鼠伤寒沙门菌致小鼠肝损伤的机制研究
沈幸玲， 丁康宁， 王幽丛， 张易安， 刘逸雷， 刘涵笑… - 中国畜牧兽医, 2022 - chvm.net
[目的] 探讨火炭母口服液对鼠伤寒沙门菌感染小鼠肝脏的保护作用及其机制.[方法] 将48
只雄性BALB/c 小鼠随机分为6 组: 空白对照组, 模型组, 阳性药物组及火炭母高, 中, 低剂量组 …
只雄性BALB/c 小鼠随机分为6 组: 空白对照组, 模型组, 阳性药物组及火炭母高, 中, 低剂量组 …
Defining the Epigenetic and Transcriptional Regulatory Mechanisms by Which hRSV NS1 Alters Host Transcriptional Response
N Beri - 2022 - search.proquest.com
WASHINGTON UNIVERSITY IN ST. LOUIS Division of Biology and Biomedical Sciences Molecular
Genetics and Genomics Dissertation Exam Page 1 WASHINGTON UNIVERSITY IN ST. LOUIS …
Genetics and Genomics Dissertation Exam Page 1 WASHINGTON UNIVERSITY IN ST. LOUIS …