[HTML][HTML] Polymersomes as a potential platform for cancer immunotherapy

JF Scheerstra, AC Wauters, J Tel… - Materials Today …, 2022 - Elsevier
With the focus in the field of cancer nanomedicine shifting from direct tumor targeting to
modulation of the immune system, new opportunities arise for the employment of …

Adjuvant-protein conjugate vaccine with built-in TLR7 agonist on S1 induces potent immunity against SARS-CoV-2 and variants of concern

RY Zhang, SH Zhou, CB He, J Wang… - ACS Infectious …, 2022 - ACS Publications
With the global pandemic of the new coronavirus disease (COVID-19), a safe, effective, and
affordable mass-produced vaccine remains the current focus of research. Herein, we …

Shaping neonatal immunization by tuning the delivery of synergistic adjuvants via nanocarriers

S Barman, F Borriello, B Brook, C Pietrasanta… - ACS chemical …, 2022 - ACS Publications
Adjuvanted nanocarrier-based vaccines hold substantial potential for applications in novel
early-life immunization strategies. Here, via mouse and human age-specific in vitro …

Multivalent Vaccine Strategies in Battling the Emergence of COVID-19 Variants

PC Guest - … Biomarker Techniques: Methods and Applications for …, 2022 - Springer
The emergence of new SARS-CoV-2 variants has led to increased transmission and more
severe cases of COVID-19, with some having the ability to escape the existing vaccines …

[HTML][HTML] Protein-protein conjugation enhances the immunogenicity of SARS-CoV-2 receptor-binding domain (RBD) vaccines

PV Scaria, CG Rowe, BB Chen, TH Dickey, JP Renn… - Iscience, 2022 - cell.com
Several effective SARS-CoV-2 vaccines have been developed using different technologies.
Although these vaccines target the isolates collected early in the pandemic, many have …

[HTML][HTML] DENV-mimetic polymersome nanoparticles bearing multi-epitope lipopeptides antigen as the next-generation Dengue vaccine

NA Abdul Rahman, AS Mohamad Norpi, ML Nordin… - Pharmaceutics, 2022 - mdpi.com
Dengue remains a severe threat to public health. The safety and efficacy of the licensed
dengue vaccine is not clinically satisfactory, which necessitate the need of new approach in …

[HTML][HTML] Polymerized porin as a novel delivery platform for coronavirus vaccine

Z Yang, L Hua, M Yang, W Li, Z Ren, X Zheng… - Journal of …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), seriously threatens human life and health. The …