Genetic generalized epilepsies in adults—challenging assumptions and dogmas
BJ Vorderwülbecke, B Wandschneider… - Nature Reviews …, 2022 - nature.com
Genetic generalized epilepsy (GGE) syndromes start during childhood or adolescence, and
four commonly persist into adulthood, making up 15–20% of all cases of epilepsy in adults …
four commonly persist into adulthood, making up 15–20% of all cases of epilepsy in adults …
Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression
Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations,
but associations between neurobiological mechanisms and macroscale connectomics …
but associations between neurobiological mechanisms and macroscale connectomics …
Drug resistance in idiopathic generalized epilepsies: Evidence and concepts
J Gesche, CP Beier - Epilepsia, 2022 - Wiley Online Library
Abstract Although approximately 10%–15% of patients with idiopathic generalized epilepsy
(IGE)/genetic generalized epilepsy remain drug‐resistant, there is no consensus or …
(IGE)/genetic generalized epilepsy remain drug‐resistant, there is no consensus or …
Relay and higher-order thalamic nuclei show an intertwined functional association with cortical-networks
VJ Kumar, CF Beckmann, K Scheffler… - Communications …, 2022 - nature.com
Almost all functional processing in the cortex strongly depends on thalamic interactions.
However, in terms of functional interactions with the cerebral cortex, the human thalamus …
However, in terms of functional interactions with the cerebral cortex, the human thalamus …
Episodic memory network connectivity in temporal lobe epilepsy
Objective Temporal lobe epilepsy (TLE) affects brain networks and is associated with
impairment of episodic memory. Temporal and extratemporal reorganization of memory …
impairment of episodic memory. Temporal and extratemporal reorganization of memory …
Centromedian nucleus of the thalamus deep brain stimulation for genetic generalized epilepsy: a case report and review of literature
S Agashe, D Burkholder, K Starnes… - Frontiers in Human …, 2022 - frontiersin.org
There is a paucity of treatment options for cognitively normal individuals with drug resistant
genetic generalized epilepsy (GGE). Centromedian nucleus of the thalamus (CM) deep …
genetic generalized epilepsy (GGE). Centromedian nucleus of the thalamus (CM) deep …
[HTML][HTML] Development and validation of MRI-based radiomics models for diagnosing juvenile myoclonic epilepsy
Objective Radiomic modeling using multiple regions of interest in MRI of the brain to
diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed …
diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed …
Aberrant dynamic structure–function relationship of rich‐club organization in treatment‐naïve newly diagnosed juvenile myoclonic epilepsy
G Liu, W Zheng, H Liu, M Guo, L Ma, W Hu… - Human brain …, 2022 - Wiley Online Library
Neuroimaging studies have shown that juvenile myoclonic epilepsy (JME) is characterized
by impaired brain networks. However, few studies have investigated the potential …
by impaired brain networks. However, few studies have investigated the potential …
More than just statics: Static and temporal dynamic changes in intrinsic brain activity in unilateral temporal lobe epilepsy
C Song, X Zhang, S Han, K Ma, K Wang… - Frontiers in Human …, 2022 - frontiersin.org
Background Temporal lobe epilepsy (TLE) is the most prevalent refractory focal epilepsy
and is more likely accompanied by cognitive impairment. The fully understanding of the …
and is more likely accompanied by cognitive impairment. The fully understanding of the …
Altered structural brain networks in refractory and nonrefractory idiopathic generalized epilepsy
A McKavanagh, BAK Kreilkamp, Y Chen… - Brain …, 2022 - liebertpub.com
Introduction: Idiopathic generalized epilepsy (IGE) is a collection of generalized nonlesional
epileptic network disorders. Around 20–40% of patients with IGE are refractory to antiseizure …
epileptic network disorders. Around 20–40% of patients with IGE are refractory to antiseizure …