Ficus exasperata Attenuates Acetaminophen‐Induced Hepatic Damage via NF‐κB Signaling Mechanism in Experimental Rat Model

BO Adetuyi, OA Adebisi, OA Adetuyi… - BioMed research …, 2022 - Wiley Online Library
Ficus exasperata has been used to treat ulcer, diabetes, fever, and a variety of stress‐
related disorders. Acetaminophen (APAP) overdose is the most common cause of drug …

Platanosides, a potential botanical drug combination, decrease liver injury caused by acetaminophen overdose in mice

DJ Samuvel, NT Nguyen, H Jaeschke… - Journal of natural …, 2022 - ACS Publications
Oxidative stress plays an important role in acetaminophen (APAP)-induced hepatotoxicity.
Platanosides (PTSs) isolated from the American sycamore tree (Platanus occidentalis) …

[HTML][HTML] Ameliorative effect of ethanolic extract of Limnophila rugosa (Scrophulariaceae) in paracetamol- and carbon tetrachloride-induced hepatotoxicity in rats

RN Hota, BK Nanda, BR Behera, A Bose - Future Journal of …, 2022 - Springer
Abstract Background Limnophila rugosa (Scrophulariaceae) is a perennial aquatic plant
used as a diuretic and digestive tonic as well as in the treatment of diarrhea, dysentery …

[PDF][PDF] Evaluation of the effects of curcumin, erdosteine, vitamin E and vitamin C on paracetamol toxicity

N Basol, C Ozmen, S Ocakli, S Cetin - Medicine, 2022 - manage.effectpublishing.com
Paracetamol toxicity is one of the most common causes of drug induced toxicity in the world.
This study aims to investigate the efficacy of curcumin, erdosteine, vitamin E and vitamin C …

Role of caspase-8 and/or-9 as biomarkers that can distinguish the potential to cause toxic-and immune related-adverse event, for the progress of acetaminophen …

T Noda, R Kato, T Hattori, Y Furukawa, Y Ijiri, K Tanaka - Life Sciences, 2022 - Elsevier
Aims Acetaminophen (APAP) overdose can cause acute liver failure. Although it is well
known that APAP-induced liver injury (AILI) is caused by toxic mechanism, recently it is also …

[HTML][HTML] Carum carvi Modulates Acetaminophen-Induced Hepatotoxicity: Effects on TNF-α, NF-κB, and Caspases

TM Mir, MU Rehman, MK Ashfaq, W Qamar, R Khan… - Applied Sciences, 2022 - mdpi.com
Carum carvi is a well-known herb traditionally used as a spice in Asian countries.
Acetaminophen is a known marketed drug mainly used as an analgesic. It has been …

The concerted elevation of conjugation reactions is associated with the aggravation of acetaminophen toxicity in Akr1a-knockout mice with an ascorbate insufficiency

S Kimura, T Osaki, T Homma, S Kimura, S Kobayashi… - Life Sciences, 2022 - Elsevier
Aims Acetaminophen (APAP) is a relatively safe analgesic drug, but overdosing can cause
acute liver failure. Ingested APAP is detoxified by metabolic conversion through conjugation …

[HTML][HTML] Selective gene expression profiling contributes to a better understanding of the molecular pathways underlying the histological changes observed after …

J Arlt, S Vlaic, R Feuer, M Thomas, U Settmacher… - BMC Medical …, 2022 - Springer
Background In previous studies, five vasoactive drugs were investigated for their effect on
the recovery process after extended liver resection without observing relevant …

Assessment of the Effects of Lacteal Forte® and Vitamin B12 versus N-acetylcysteine in the Treatment of Acetaminophen‐induced Hepatorenal Toxicity

RM Saleh, MF Elshal, RA El-Shafei… - Egyptian Journal of …, 2022 - journals.ekb.eg
Acetaminophen (APAP) is one of the most frequently used analgesics and antipyretics
worldwide, however, an overdose of paracetamol is a leading cause of hepato-renal injury …

[PDF][PDF] Histological and Biochemical Investigation of Hepato-protective Role of Vitamin B12 in Male Wistar Rats Intoxicated by Diazinon

AK Hameed - Basrah Journal of Veterinary Research, 2022 - iasj.net
In order to estimate the hepato-protective activity of Vit. B12 in diazinon hepatotoxic effect,
the current study was performed on twenty-four male adult Wistar rats. They'd divided into …