Hypertension is a major cardiovascular disease risk factor and contributor to premature
death globally. Family-based investigations confirmed a significant heritable component of …

Background Single nucleotide polymorphism (SNP) variants are abundant, persistent and
widely distributed across the genome and are frequently linked to the development of …

Objective: Carotid artery intima-media thickness (cIMT) is a widely accepted marker of
subclinical atherosclerosis. Twenty susceptibility loci for cIMT were previously identified and …

Background: The availability of whole-genome sequencing data in large studies has
enabled the assessment of coding and noncoding variants across the allele frequency …

The aim of this study was to explore the effects of pre-pregnancy overweight/obesity on the
pattern of association of hypertension susceptibility genes with preeclampsia (PE). Ten …

Abstract Purpose of Review Arterial stiffness (AS) was mainly associated with cardiovascular
morbidity and mortality in a hypertensive patient. Some risk factors contribute to the …

People with coronavirus disease 2019 (COVID-19) have different mortality or severity, and
this clinical outcome is thought to be mainly attributed to comorbid cardiovascular diseases …

Accumulating evidence suggested that long non-coding RNAs (lncRNAs) could play
biological roles in cardiovascular diseases. We investigated whether lncRNAs can serve as …

Hypertension is a leading risk factor for cardiovascular disease mortality. African Americans
(AAs) have the highest prevalence of hypertension in the United States, and to alleviate the …

Background Corin enzyme contributes to the processing of inactive natriuretic peptides to
bioactive hormones. In Black individuals, Corin gene variants (rs111253292 [Q568P] and …