[HTML][HTML] High-density lipoproteins: a role in inflammation in COPD

S Kotlyarov - International Journal of Molecular Sciences, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a widespread disease associated with
high rates of disability and mortality. COPD is characterized by chronic inflammation in the …

[HTML][HTML] Involvement of the innate immune system in the pathogenesis of chronic obstructive pulmonary disease

S Kotlyarov - International Journal of Molecular Sciences, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a common, socially significant disease
characterized by progressive airflow limitation due to chronic inflammation in the bronchi …

[HTML][HTML] Extracellular release of mitochondrial DNA: triggered by cigarette smoke and detected in COPD

L Giordano, AD Gregory, M Pérez Verdaguer, SA Ware… - Cells, 2022 - mdpi.com
Cigarette smoke (CS) is the most common risk factor for chronic obstructive pulmonary
disease (COPD). The present study aimed to elucidate whether mtDNA is released upon CS …

[HTML][HTML] TLR/WNT: A novel relationship in immunomodulation of lung cancer

A Martín-Medina, N Cerón-Pisa… - International Journal of …, 2022 - mdpi.com
The most frequent cause of death by cancer worldwide is lung cancer, and the 5-year
survival rate is still very poor for patients with advanced stage. Understanding the crosstalk …

Sex differences and altered mitophagy in experimental pulmonary hypertension

IS Bazan, SJ Kim, TA Ardito, Y Zhang… - … of Physiology-Lung …, 2022 - journals.physiology.org
Pulmonary hypertension (PH) is a debilitating condition characterized by increased
pulmonary arterial pressures and remodeling of pulmonary arteries, leading to right heart …

[HTML][HTML] Aging, tobacco use and lung damages

S Rouatbi - La Tunisie Médicale, 2022 - ncbi.nlm.nih.gov
The main two functions of the lung are the respiratory functions, dependent on ventilatory
mechanics and gas exchange, and the non-respiratory functions such as metabolic …

[HTML][HTML] Cereblon Deficiency Contributes to the Development of Elastase-Induced Emphysema by Enhancing NF-κB Activation

EY Heo, KH Lee, J Woo, J Kim, CH Lee, KJ Lee… - Antioxidants, 2022 - mdpi.com
Cereblon (CRBN) has been shown to play an essential role in regulating inflammatory
response and endoplasmic reticulum stress, thus mediating the development of various …