Genome-wide sequencing has led to the discovery of thousands of long non-coding RNA
(lncRNA) loci in the human genome, but evidence of functional significance has remained …

DNA methylation is one of the most important epigenetic mechanisms that governing
regulation of gene expression, aberrant DNA methylation patterns are strongly associated …

Eukaryotic cells can initiate several distinct self‐destruction mechanisms to display essential
roles for the homeostasis maintenance, development, and survival of an organism …

Human papillomavirus (HPV)-negative tumors distinguish from cancers associated with HPV
infection. Due to its high rate of lymph node metastasis and difficulty in inchoate discover …

Long noncoding RNAs (lncRNAs) are products of pervasive transcription that closely
resemble messenger RNAs on the molecular level, yet function through largely unknown …

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. Metabolic
reprogramming is considered to be an important hallmark of cancer. Emerging studies have …

Abstract Long noncoding RNAs (LncRNAs) have emerged as a diverse class of functional
molecules that contribute to nearly every facet of mammalian cardiac development and …

Breast cancer (BC) is a highly complex and heterogenous disease. Several oncogenic
signaling pathways drive BC oncogenic activity, thus hindering scientists to unravel the …

Emerging evidence has suggested that N 6‑methyladenosine (m6A) modification, a typical
RNA methylation modification, controls the fate of modified transcripts and is involved in the …

Background The development of heart ageing is the main cause of chronic disability,
disease and death in the elderly. Ample evidence has established a pivotal role for …