Polycomb group proteins predominantly exist in polycomb repressive complexes (PRCs)
that cooperate to maintain the repressed state of thousands of cell-type-specific genes …

The Polycomb repressive complex 2 (PRC2) is an essential chromatin regulatory complex
involved in repressing the transcription of diverse developmental genes. PRC2 consists of a …

Fibroblast growth factor (FGF) is a neural inducer in many vertebrate embryos, but how it
regulates chromatin organization to coordinate the activation of neural genes is unclear …

Adult mammalian cardiomyocytes have very limited capacity to proliferate and repair the
myocardial infarction. However, when apical resection (AR) was performed in pig hearts on …

Embryonic stem cells (ESCs) are a type of cells capable of self-renewal and multi-directional
differentiation. The self-renewal of ESCs is regulated by factors including signaling pathway …

Summary Polycomb repressive complex 2 (PRC2) methylates histone H3 lysine 27
(H3K27me3) to maintain gene repression and is essential for cell differentiation. In low …

Pluripotent cells have been stabilized from pre-and post-implantation blastocysts,
representing respectively naïve and primed stages of embryonic stem cells (ESCs) with …

Simple Summary Sow reproductive performance is crucial in the entire pig industry.
However, the heritability of reproductive traits is slowthat it is difficult to make great genetic …

Background Deletions covering the entire or partial JARID2 gene as well as pathogenic
single nucleotide variants leading to haploinsufficiency of JARID2 have recently been …

Некомпактный миокард левого желудочка (НКМЛЖ)–редко встречающаяся
разновидность первичных генетических или неклассифицируемых кардиомиопатий …