[HTML][HTML] The role of Hsp90-R2TP in macromolecular complex assembly and stabilization

J Lynham, WA Houry - Biomolecules, 2022 - mdpi.com
Hsp90 is a ubiquitous molecular chaperone involved in many cell signaling pathways, and
its interactions with specific chaperones and cochaperones determines which client proteins …

Compound heterozygous variants in SHQ1 are associated with a spectrum of neurological features, including early-onset dystonia

S Sleiman, AE Marshall, X Dong… - Human Molecular …, 2022 - academic.oup.com
SHQ1 is essential for biogenesis of H/ACA ribonucleoproteins, a class of molecules
important for processing ribosomal RNAs, modifying spliceosomal small nuclear RNAs and …

[PDF][PDF] Mechanistic characterization of pseudouridine formation by eukaryotic H/ACA snoRNPs

MGD Namala - 2022 - opus.uleth.ca
ABSTRACT The H/ACA snoRNP complex directs the formation of pseudouridines in
ribosomal RNA (rRNA); however, the mechanisms by which the eukaryotic two-hairpin …