Numerous tissues in the human body have fibrous structures, including the extracellular
matrix, muscles, and heart, which perform critical biological functions and have exceptional …

Computational modelling of damage and rupture of non-connective and connective soft
tissues due to pathological and supra-physiological mechanisms is vital in the fundamental …

Data-driven methods are becoming an essential part of computational mechanics due to
their advantages over traditional material modeling. Deep neural networks are able to learn …

Aortic dissection progresses mainly via delamination of the medial layer of the wall.
Notwithstanding the complexity of this process, insight has been gleaned by studying in vitro …

Closed-form constitutive models are currently the standard approach for describing soft
tissues' mechanical behavior. However, there are inherent pitfalls to this approach. For …

Experimental data and a suitable material model for human aortas with smooth muscle
activation are not available in the literature despite the need for developing advanced grafts; …

In this contribution, we propose a novel continuum mechanical concept to determine the
homogenised mechanical response of random fibre networks. Their free energy is …

This study investigated the effects of different patterns of coronary artery tortuosity (CAT) on
the stress concentration of the plaques and the blood flow pattern inside an atherosclerotic …

Artificial tissues made of fiber-reinforced polymeric materials typically show biological tissue-
like mechanical properties, which motivates its usage in designing and constructing human …

The analysis of tissue mechanics in biomedical applications demands nonlinear constitutive
models able to capture the energy dissipation mechanisms, such as damage, that occur …