Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment
S Qi, N Duan, IM Khan, X Dong, Y Zhang, S Wu… - Biotechnology …, 2022 - Elsevier
Aptamers are short single-stranded DNA or RNA oligonucleotides isolated from randomized
libraries, presenting high affinity and specificity toward targets with similar to antibodies …
libraries, presenting high affinity and specificity toward targets with similar to antibodies …
A comprehensive review of oyster peptides: Preparation, characterisation and bioactivities
L Hao, X Wang, Y Cao, J Xu, C Xue - Reviews in Aquaculture, 2022 - Wiley Online Library
Oysters are a healthy and excellent source of lean protein (content up to 45%–57%). In
addition, polypeptides extracted from hydrolysis of oyster protein by enzymatic hydrolysis or …
addition, polypeptides extracted from hydrolysis of oyster protein by enzymatic hydrolysis or …
[HTML][HTML] Technological interventions in improving the functionality of proteins during processing of meat analogs
Meat analogs have opened a new horizon of opportunities for developing a sustainable
alternative for meat and meat products. Proteins are an integral part of meat analogs and …
alternative for meat and meat products. Proteins are an integral part of meat analogs and …
Peptidomimetics in cancer targeting
The low efficiency of treatment strategies is one of the main obstacles to developing cancer
inhibitors. Up to now, various classes of therapeutics have been developed to inhibit cancer …
inhibitors. Up to now, various classes of therapeutics have been developed to inhibit cancer …
Toxicity of trastuzumab for breast cancer spheroids: application of a novel on-a-chip concentration gradient generator
Evaluating the effectiveness of drugs on an individual basis before prescribing them has an
influential role in choosing a successful treatment plan. The advent of microfluidic devices …
influential role in choosing a successful treatment plan. The advent of microfluidic devices …
Evaluation of pH change effects on the HSA folding and its drug binding characteristics, a computational biology investigation
The binding of therapeutics to human serum albumin (HSA), which is an abundant protein in
plasma poses a major challenge in drug discovery. Although HSA has several binding …
plasma poses a major challenge in drug discovery. Although HSA has several binding …
Engineering his-tagged senecavirus a for one-step purification of viral antigens
J Fan, P Xiao, D Kong, X Liu, L Meng, T An, X Cai… - Vaccines, 2022 - mdpi.com
Senecavirus A (SVA) is a picornavirus that causes vesicular disease in swine, and the
inactivated vaccine is used to prevent and control SVA infection. To develop a new …
inactivated vaccine is used to prevent and control SVA infection. To develop a new …
A cleavable self-aggregating tag scheme for the expression and purification of disulfide bonded proteins and peptides
The production of correctly folded, disulfide bonded proteins in high yields remains a
technological challenge, especially for the commonly used expression system Escherichia …
technological challenge, especially for the commonly used expression system Escherichia …
Recent advances in siRNA delivery systems for prostate cancer therapy
S Aghamiri, P Raee… - Current …, 2022 - ingentaconnect.com
The critical problems of conventional prostate cancer therapeutic strategies like nonspecific
toxicity and multi-drug resistance prompted the development and application of countless …
toxicity and multi-drug resistance prompted the development and application of countless …
[HTML][HTML] Expression, purification, and kinetic characterization of the human strep-IDO1
D Saimi, Z Wang, Q Zhu, J Lv - Translational Cancer Research, 2022 - ncbi.nlm.nih.gov
Background Tryptophan catabolism leading to T cell suppression mediated by indoleamine
2, 3-dioxygenase (IDO1) is an important mechanism of tumor immune escape, and IDO1 …
2, 3-dioxygenase (IDO1) is an important mechanism of tumor immune escape, and IDO1 …