The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

TH Karlsen, N Sheron, S Zelber-Sagi, P Carrieri… - The Lancet, 2022 - thelancet.com
Executive summary Liver diseases have become a major health threat across Europe, and
the face of European hepatology is changing due to the cure of viral hepatitis C and the …

NAFLD-driven HCC: Safety and efficacy of current and emerging treatment options

F Foerster, SJ Gairing, L Müller, PR Galle - Journal of hepatology, 2022 - Elsevier
In light of a global rise in obesity and type 2 diabetes, non-alcoholic fatty liver disease
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

BS Sheena, L Hiebert, H Han, H Ippolito… - The lancet …, 2022 - thelancet.com
Background Combating viral hepatitis is part of the UN Sustainable Development Goals
(SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector …

Pathogenesis and current treatment strategies of hepatocellular carcinoma

D Tümen, P Heumann, K Gülow, CN Demirci… - Biomedicines, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the most frequent liver cancer with high lethality and low
five-year survival rates leading to a substantial worldwide burden for healthcare systems …

[HTML][HTML] Viral hepatitis: Past, present, and future

MA Odenwald, S Paul - World journal of gastroenterology, 2022 - ncbi.nlm.nih.gov
Each hepatitis virus—Hepatitis A, B, C, D, E, and G—poses a distinct scenario to the patient
and clinician alike. Since the discovery of each virus, extensive knowledge regarding …

The global impact of hepatitis B vaccination on hepatocellular carcinoma

JE Flores, AJ Thompson, M Ryan, J Howell - Vaccines, 2022 - mdpi.com
Over 1.5 million preventable new hepatitis B infections continue to occur each year and
there are an estimated 296 million people living with chronic hepatitis B infection worldwide …

[HTML][HTML] Viral hepatitis and hepatocellular carcinoma: From molecular pathways to the role of clinical surveillance and antiviral treatment

L Stella, F Santopaolo, A Gasbarrini… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a global health challenge. Due to the high prevalence in
low-income countries, hepatitis B virus (HBV) and hepatitis C virus infections remain the …

[HTML][HTML] What to do about hepatocellular carcinoma: Recommendations for health authorities from the International Liver Cancer Association

M Allaire, J Bruix, M Korenjak, S Manes, Z Maravic… - JHEP Reports, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is a major public health problem worldwide for which the
incidence and mortality are similar, pointing to the lack of effective treatment options …

Direct-acting antiviral agents for hepatitis C virus infection—From drug discovery to successful implementation in clinical practice

C Dietz, B Maasoumy - Viruses, 2022 - mdpi.com
Today, hepatitis C virus infection affects up to 1.5 million people per year and is responsible
for 29 thousand deaths per year. In the 1970s, the clinical observation of unclear, transfusion …

[HTML][HTML] Epidemiologic and socioeconomic factors impacting hepatitis B virus and related hepatocellular carcinoma

B Gnyawali, A Pusateri, A Nickerson… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Chronic Hepatitis B is a highly prevalent disease worldwide and is estimated to cause more
than 800000 annual deaths from complications such as cirrhosis and hepatocellular …