A novel circRNA-miRNA association prediction model based on structural deep neural network embedding

LX Guo, ZH You, L Wang, CQ Yu… - Briefings in …, 2022 - academic.oup.com
A large amount of clinical evidence began to mount, showing that circular ribonucleic acids
(RNAs; circRNAs) perform a very important function in complex diseases by participating in …

GLS1 is a protective factor in patients with ovarian clear cell carcinoma and its expression does not correlate with ARID1A-mutated tumors

V Clemente, A Hoshino, M Shetty, A Nelson… - Cancer research …, 2022 - AACR
Targeting glutamine metabolism has emerged as a novel therapeutic strategy for several
human cancers, including ovarian cancer. The primary target of this approach is the kidney …

[HTML][HTML] Effect of short-term high fat diet on resistin levels and expression of autophagy-related genes in the cartilage of male rats

HM Aboudeya, SA Shaker, M Salama - Scientific Reports, 2022 - nature.com
Obesity is a significant risk factor for the development of knee osteoarthritis (KOA). However,
the precise molecular mechanisms linking obesity to OA remain unclear. In the present …

The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility

Y Zhao, Q Zhang, X Zhang, Y Zhang, Y Lu… - Brain and …, 2022 - Wiley Online Library
Background Ischemic stroke (IS), a multifactorial and polygenic disease, is the most common
cause of death. This study aimed to determine the roles of MMP8/MMP10 polymorphisms in …

Exploration of the Components and Pharmacological Mechanisms of Keyin Pill‐Induced Liver Injury Based on Network Pharmacology

B Xing, Y Cui, Y Chen, L Lai, M Zhang… - Evidence‐Based …, 2022 - Wiley Online Library
Background. Keyin pill (KP), a patented medicine in China, is used to treat psoriasis.
However, KP has been reported to have liver toxicity, but its toxic substance basis and …