DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp

F Zheng, RE Georgescu, NY Yao… - Nature structural & …, 2022 - nature.com
Abstract The 9-1-1 DNA checkpoint clamp is loaded onto 5′-recessed DNA to activate the
DNA damage checkpoint that arrests the cell cycle. The 9-1-1 clamp is a heterotrimeric ring …