Molecular genetics and targeted therapies for paediatric high-grade glioma
KS Rallis, AM George, AM Wozniak… - Cancer Genomics & …, 2022 - cgp.iiarjournals.org
Brain tumours are the leading cause of paediatric cancer-associated death worldwide. High-
grade glioma (HGG) represents a main cause of paediatric brain tumours and is associated …
grade glioma (HGG) represents a main cause of paediatric brain tumours and is associated …
[HTML][HTML] Circulating tumor DNA profiling for childhood brain tumors: Technical challenges and evidence for utility
APY Liu, PA Northcott, GW Robinson, A Gajjar - Laboratory Investigation, 2022 - Elsevier
Cell-free DNA (cfDNA) profiling as liquid biopsy has proven value in adult-onset
malignancies, serving as a patient-specific surrogate for residual disease and providing a …
malignancies, serving as a patient-specific surrogate for residual disease and providing a …
Liquid biopsy: early and accurate diagnosis of brain tumor
Z Yi, C Qu, Y Zeng, Z Liu - Journal of Cancer Research and Clinical …, 2022 - Springer
Noninvasive examination is an emerging area in the field of neuro-oncology. Liquid biopsy
captures the landscape of genomic alterations of brain tumors and revolutionizes the …
captures the landscape of genomic alterations of brain tumors and revolutionizes the …
Radiomics features based on MRI predict BRAF V600E mutation in pediatric low-grade gliomas: A non-invasive method for molecular diagnosis
J Xu, M Lai, S Li, K Ye, L Li, Q Hu, R Ai, J Zhou… - Clinical Neurology and …, 2022 - Elsevier
Objective To investigate the clinical application value of radiomics features based on
preoperative magnetic resonance imaging for predicting B-Raf proto-oncogene …
preoperative magnetic resonance imaging for predicting B-Raf proto-oncogene …
[HTML][HTML] Novel CSF biomarkers tracking autoimmune inflammatory and neurodegenerative aspects of CNS diseases
E Kapaki, AG Vakrakou, F Boufidou - Diagnostics, 2022 - mdpi.com
The accurate diagnosis of neuroinflammatory (NIDs) and neurodegenerative (NDDs)
diseases and the stratification of patients into disease subgroups with distinct disease …
diseases and the stratification of patients into disease subgroups with distinct disease …
Case report and literature review of BRAF‐V600 inhibitors for treatment of papillary craniopharyngiomas: A potential treatment paradigm shift.
PE Nussbaum, LA Nussbaum… - Journal of Clinical …, 2022 - search.ebscohost.com
What is known and objective: The BRAF‐V600E genetic mutation offers a potential targeted
therapy for the treatment of papillary craniopharyngiomas. Case summary: A 35‐year‐old …
therapy for the treatment of papillary craniopharyngiomas. Case summary: A 35‐year‐old …
[HTML][HTML] Circulating tumor DNA in pediatric cancer
L Doculara, TN Trahair, N Bayat… - Frontiers in Molecular …, 2022 - frontiersin.org
The measurement of circulating tumor DNA (ctDNA) has gained increasing prominence as a
minimally invasive tool for the detection of cancer-specific markers in plasma. In adult …
minimally invasive tool for the detection of cancer-specific markers in plasma. In adult …
[HTML][HTML] Liquid biopsy in CNS tumors: current status & future perspectives
N Husain, A Husain, S Mishra… - Indian Journal of …, 2022 - journals.lww.com
Precise classification of central nervous system (CNS) malignancies is vital for the treatment
and prognostication. Identification of noninvasive markers can be of importance to guide …
and prognostication. Identification of noninvasive markers can be of importance to guide …