The ubiquity, structural variation, and functional diversity of iron-sulfur (Fe-S) clusters in
biological environments has long fascinated scientists. In nature, Fe-S clusters form a variety …

Iron–sulfur clusters are ubiquitous cofactors that mediate central biological processes.
However, despite their long history, these metallocofactors remain challenging to investigate …

In eukaryotes, iron-sulfur clusters are essential cofactors for numerous physiological
processes, but these clusters are primarily biosynthesized in mitochondria. Previous studies …

Investigations of biology and the origins of life regularly focus on the components of the
central dogma and thus the elements that compose nucleic acids and peptides. Less …

Iron‐sulfur clusters are thought to be ancient cofactors that could have played a role in early
protometabolic systems. Thus far, redox active, prebiotically plausible iron‐sulfur clusters …

Metal ions are known to catalyze certain prebiotic reactions. However, the transition from
metal ions to extant metalloenzymes remains unclear. Porphyrins are found ubiquitously in …

Wet–dry cycles driven by heating to high temperatures are frequently invoked for the
prebiotic synthesis of peptides. Similarly, iron–sulfur clusters are often cited as an example …

Independently developed iron-sulphur/thioester-and phosphate-driven chemical reactions
would have set up two distinct reaction networks prior to coupling in a proto-metabolic …

Comprehensive Summary Iron‐sulfur (Fe‐S) proteins are among the most common type of
natural metalloproteins that participate in a large range of key metabolic processes. To date …

Although peptides were widely used in many fields, their interface behaviors as surfactants
have not been explored. The results of the surface tension experiments by an automatic …