Strategies to enhance immunomodulatory properties and reduce heterogeneity in mesenchymal stromal cells during ex vivo expansion
Therapies using mesenchymal stromal cells (MSCs) to treat immune and inflammatory
conditions are now at an exciting stage of development, with many MSC-based products …
conditions are now at an exciting stage of development, with many MSC-based products …
Transplantation of human adipose-derived stem cells overexpressing LIF/IFN-β promotes recovery in experimental autoimmune encephalomyelitis (EAE)
M Yousefi, A Nabipour, M Ganjalikhani Hakemi… - Scientific Reports, 2022 - nature.com
Multiple Sclerosis (MS) is the most common demyelinating disease with inflammatory
demyelination in the central nerve system. Besides the defect in the myelin repair process …
demyelination in the central nerve system. Besides the defect in the myelin repair process …
The therapeutic potential of mesenchymal stem cells in the treatment of diabetes mellitus
L Zhu, S Wang, JS Qu, Z Hui, C Kan, N Hou… - Cellular …, 2022 - liebertpub.com
Mesenchymal stem cells (MSCs) exist in many tissues and can differentiate into cells of
multiple lineages, such as adipocytes, osteoblasts, or chondrocytes. MSC administration has …
multiple lineages, such as adipocytes, osteoblasts, or chondrocytes. MSC administration has …
The effect of poly I: C or LPS priming on the therapeutic efficacy of mesenchymal stem cells in an adjuvant-induced arthritis rat model
Background The immunomodulatory properties of mesenchymal stem cells (MSCs) have
made them a prospective treatment option for inflammatory and autoimmune disorders …
made them a prospective treatment option for inflammatory and autoimmune disorders …
The CIt protocol: A blueprint to potentiate the immunogenicity of immunoproteasome-reprogrammed mesenchymal stromal cells
JP Bikorimana, N El-Hachem, J Abusarah… - Iscience, 2022 - cell.com
Immunoproteasome-reprogrammed mesenchymal stromal cells (IRMs) can surpass
dendritic cells at eliciting tumor-specific immunity. However, the current IRM vaccination …
dendritic cells at eliciting tumor-specific immunity. However, the current IRM vaccination …
Lentivirus-mediated PD-L1 overexpression in bone marrow-derived dendritic cells induces immune tolerance in a rat keratoplasty model
R Liu, R Yi, X Chen, G Yi, M Fu - Transplant Immunology, 2022 - Elsevier
Purpose The side effects of immune suppressants on immune rejection have become
increasingly apparent after keratoplasty. To find out new alternative immunotherapy …
increasingly apparent after keratoplasty. To find out new alternative immunotherapy …
Considerations for Clinical Use of Mesenchymal Stromal Cells
The clinical application of stem cells continues to fascinate the scientific and clinical
communities. Despite the controversies surrounding this field, it is clear that stem cells have …
communities. Despite the controversies surrounding this field, it is clear that stem cells have …
[PDF][PDF] Mahdieh Yousefi1, Abolghasem Nabipour, Mazdak Ganjalikhani Hakemi2, Mehnoosh Ashja‑Arvan2, Noushin Amirpour3 & Hossein Salehi3Ε
T Tregs Regulatory - Scientific Reports, 2022 - academia.edu
Materials and methods Isolation and culture of hADSCs. Adipose tissue was obtained from
female donors aged 20 to 40 years in Al-Zahra Hospital of Isfahan with informed personal …
female donors aged 20 to 40 years in Al-Zahra Hospital of Isfahan with informed personal …
Transplantation of human adipose derived stem cells with co-overexpressed Leukemia inhibitory factor and beta interferon promote recovery in experimental …
M Yoosefi, A Nabipour… - Available at SSRN …, 2022 - papers.ssrn.com
Multiple Sclerosis (MS) is the most common demyelinating disease with inflammatory
demyelination in central nerve system (CNS). Beside the defect in myelin repair process, the …
demyelination in central nerve system (CNS). Beside the defect in myelin repair process, the …
Mesenchymal stromal cells and uses related thereto
EA Kimbrel, RP Lanza, J Chu… - US Patent App. 17 …, 2022 - Google Patents
The present invention generally relates to novel preparations of mesenchymal stromal cells
(MSCs) derived from hemangioblasts, methods for obtaining such MSCs, and methods of …
(MSCs) derived from hemangioblasts, methods for obtaining such MSCs, and methods of …