Nrf2 and oxidative stress in liver ischemia/reperfusion injury

R G. Bardallo, A Panisello‐Roselló… - The FEBS …, 2022 - Wiley Online Library
In response to stress signal, nuclear factor‐erythroid 2‐related factor 2 (Nrf2) induces the
expression of target genes involved in antioxidant defense and detoxification. Nrf2 activity is …

NRF2 and key transcriptional targets in melanoma redox manipulation

EL Carpenter, AL Becker, AK Indra - Cancers, 2022 - mdpi.com
Simple Summary Melanocytes are the pigment-producing cells in the skin that help to
protect it against damaging solar ultraviolet radiation. As they engage in this function, they …

Recent advances in the role of nuclear factor erythroid-2-related factor 2 in spinal cord injury: regulatory mechanisms and therapeutic options

T Jiang, Y He - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Nuclear factor erythroid-2-related factor 2 (Nrf2) is a pleiotropic transcription factor, and it
has been documented that it can induce defense mechanisms both oxidative stress and …

HSF1 and its role in Huntington's disease pathology

H Kim, R Gomez-Pastor - Cell Biology and Translational Medicine, Volume …, 2022 - Springer
Purpose of review: Heat shock factor 1 (HSF1) is the master transcriptional regulator of the
heat shock response (HSR) in mammalian cells and is a critical element in maintaining …

Basic Leucine Zipper Protein Nuclear Factor Erythroid 2–related Factor 2 as a Potential Therapeutic Target in Brain Related Disorders

A Goyal, S Gopika, N Agrawal - Protein and Peptide Letters, 2022 - ingentaconnect.com
Nuclear factor erythroid-2-related factor 2 (Nrf2), an inducible transcription factor in phase II
metabolic reactions, as well as xenobiotic response pathway, is referred to as 'master …

Regulation of Redox Homeostasis in Skin Cells for the Prevention of UV-Induced Stress and Treatment of Melanoma

EL Carpenter - 2022 - ir.library.oregonstate.edu
Melanocytes are dendritic, pigment-producing cells located in the skin and are responsible
for its protection against the deleterious effects of solar ultraviolet radiation (UVR), which …