[HTML][HTML] From empirical to pathogenesis-based treatments for psoriasis

PCM van de Kerkhof - Journal of Investigative Dermatology, 2022 - Elsevier
Since the foundation of the European Society for Dermatological Research, pathogenesis of
psoriasis has been studied by many research groups, focusing on various compartments of …

Targeted systemic therapies for psoriatic arthritis: a systematic review and comparative synthesis of short-term articular, dermatological, enthesitis and dactylitis …

IB McInnes, LM Sawyer, K Markus, C LeReun… - RMD open, 2022 - rmdopen.bmj.com
Introduction Randomised controlled trials (RCTs) have compared biological and targeted
systemic disease-modifying antirheumatic drugs (DMARDS) against placebo in psoriatic …

Biologics‐loaded photothermally dissolvable hyaluronic acid microneedle patch for psoriasis treatment

D Wu, X Shou, Y Yu, X Wang, G Chen… - Advanced Functional …, 2022 - Wiley Online Library
Emerging biologics, such as monoclonal antibodies (mAbs), are the most promising
treatment for psoriasis, while their effective delivery to the local inflammatory area of the skin …

Risankizumab treatment in psoriasis patients who failed anti‐IL17: a 52‐week real‐life study

M Megna, L Potestio, A Ruggiero… - Dermatologic …, 2022 - Wiley Online Library
Recent knowledge on the key role of interleukin (IL) 23/17 axis in psoriasis pathogenesis,
led to development of new biologic drugs. Risankizumab is a humanized immunoglobulin …

[HTML][HTML] [Translated article] Practical Update of the Recommendations Published by the Psoriasis Group of the Spanish Academy of Dermatology and Venereology …

JM Carrascosa, L Puig, IB Romero… - Actas dermo …, 2022 - Elsevier
Background and objectives A new, updated AEDV Psoriasis Group (GPs) consensus
document on the treatment of moderate to severe psoriasis was needed owing to the …

Long-term benefit–risk profiles of treatments for moderate-to-severe plaque psoriasis: a network meta-analysis

AW Armstrong, AM Soliman, KA Betts, Y Wang… - Dermatology and …, 2022 - Springer
Introduction The long-term benefit–risk profiles of licensed and investigational treatments for
moderate-to-severe plaque psoriasis have not been fully characterized. Methods …

The role of IL‐23 and the use of IL‐23 inhibitors in psoriatic arthritis

GE Fragoulis, S Siebert - Musculoskeletal Care, 2022 - Wiley Online Library
Abstract Background Psoriatic arthritis (PsA) is a chronic inflammatory arthritis characterised
by musculoskeletal and extra‐articular manifestations, most notably psoriasis. While the …

Efficacy, safety, and drug survival of patients with psoriasis treated with IL-17 inhibitors–brodalumab, ixekizumab, and secukinumab: real-world data from the Czech …

M Kojanova, J Hugo, B Velackova… - Journal of …, 2022 - Taylor & Francis
Background Real-world data on the use of interleukin-17 (IL-17) inhibitors for the treatment
of psoriasis are limited. Objective To evaluate and compare the efficacy, safety, and drug …

An update on emerging immunological targets and their inhibitors in the treatment of psoriasis

S Parab, G Doshi - International immunopharmacology, 2022 - Elsevier
Psoriasis is a non-communicable, heterogeneous, autoimmune, inflammatory skin disease
characterised by reddish, scaly plaques that grow over time. Psoriasis affects people in all …

Network meta-analysis comparing the efficacy of biologic treatments for achieving complete resolution of nail psoriasis

K Reich, C Conrad, LE Kristensen… - Journal of …, 2022 - Taylor & Francis
Background Nail psoriasis (NP) is common and of high importance in patients with psoriasis.
Complete resolution of NP at week 24‒26 is an unambiguous nail outcome accessible for …