Highlights•Metabolomics has become a widely applied tool in drug development.•
Metabolomics plays a key role for the identification of physiological response markers.• …

New mass spectrometry imaging (MSI) techniques are gaining importance in various stages
of the drug discovery and development chain as well as in more fundamental studies of drug …

In addition to individual imaging techniques, the combination and integration of several
imaging techniques, so-called multimodal imaging, can provide large amounts of …

Revealing the metabolic abnormalities of central and peripheral systems in Alzheimer's
disease (AD) mouse model is of paramount importance for understanding AD disease …

Mass spectrometry imaging (MSI) is a tool capable of simultaneously providing in situ
untargeted chemical information as well as the spatial distribution of vast molecular species …

Mass spectrometry imaging (MSI) is a powerful technique that combines the ability of
microscopy to provide spatial information about multiple molecular species with the …

Mass spectrometry imaging (MSI) has been applied for label‐free three‐dimensional (3D)
imaging from position array across the whole organism, which provides high‐dimensional …

Human physiological activities and pathological changes arise from the coordinated
interactions of multiple molecules. Mass spectrometry (MS)-based multi-omics and MS …

The potential of mass spectrometry imaging (MSI) has been demonstrated in cell and tissue
research since 1970. MSI can reveal the spatial distribution of a wide range of atomic and …

Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly
every stage of the preclinical drug research and development (R&D) pipeline, and even to …