The term ferroptosis was put forward in 2012 and has been researched exponentially over
the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed …

Breast cancer represents a heterogeneous group of human cancer at both histological and
molecular levels. Estrogen receptor (ER), progesterone receptor (PR) and human epidermal …

Simple Summary Late-stage colorectal cancer treatment often involves chemotherapy and
radiation that can cause dose-limiting toxicity, and therefore there is great interest in …

Immune-checkpoint inhibitors targeting the PD-1/PD-L1 axis have brought significant clinical
benefit in many solid cancer types, including gastrointestinal malignancies. However, it has …

Abstract Programmed cell death‐1 (PD‐1) and its ligand (PD‐L1) are significant mediators
of immune suppression in the tumor microenvironment. We focused on the immunological …

Oral squamous cell carcinoma (OSCC) is one of the most prevalent forms of head and neck
cancer, and it remains a leading cause of death in developing countries. Failure to detect the …

Background We investigate the correlation between programmed cell death-ligand 1 (PD-
L1) and tumor-associated immune cell (TAIC) density in small-cell neuroendocrine …

Glioblastoma is the most malignant primary glioma. Conventional treatment methods that
include surgery, radiotherapy, and chemotherapy have a limited curative effect on the tumor …

In the era of immune checkpoint inhibitors, understanding the metastatic microenvironment
of proficient mismatch repair/microsatellite stable (pMMR/MSS) colorectal cancer (CRC) is of …

Background Few studies have addressed the clinicopathological features of colorectal
cancer (CRC) that express programed death-ligand 1 (PD-L1). Various assays and scoring …