Fedratinib, the first selective JAK2 inhibitor approved for treatment of myelofibrosis–an option beyond ruxolitinib

C Saha, C Harrison - Expert Review of Hematology, 2022 - Taylor & Francis
Introduction Myelofibrosis, a life shortening clonal disorder, presents with a constellation of
features: bone marrow fibrosis, abnormal blood counts, extramedullary hematopoiesis …

Efficacy and safety of ropeginterferon alfa-2b in Japanese patients with polycythemia vera: an open-label, single-arm, phase 2 study

Y Edahiro, K Ohishi, A Gotoh, K Takenaka… - International journal of …, 2022 - Springer
Ropeginterferon alfa-2b is a novel, site-selective, monopegylated recombinant human
interferon alfa-2b. Safety and efficacy of ropeginterferon alfa-2b for the treatment of …

[HTML][HTML] TGF-β signaling in myeloproliferative neoplasms contributes to myelofibrosis without disrupting the hematopoietic niche

JC Yao, KA Oetjen, T Wang, H Xu… - The Journal of …, 2022 - Am Soc Clin Investig
Myeloproliferative neoplasms (MPNs) are associated with significant alterations in the bone
marrow microenvironment that include decreased expression of key niche factors and …

Development of multiple myeloma after 15 years of treatment for polycythemia vera and successful treatment using bortezomib: A case report

H Kimura, M Furukawa, H Mori, Y Shiga… - Clinical Case …, 2022 - Wiley Online Library
Multiple myeloma (MM) and polycythemia vera (PV) rarely coexist; the clinical
manifestations and treatment of this coexistence have not been described. An 81‐year‐old …

[HTML][HTML] Novel ATM Gene c.5644 C > T (p.Arg1882*) Variant Detected in a Patient with Pancreatic Adenocarcinoma and Two Primary Non-Small Cell Lung …

AA Aljamal, MK Elajami, EH Mansour, HF Bahmad… - Diseases, 2022 - mdpi.com
Ataxia-telangiectasia is an autosomal recessive disorder that usually manifests in childhood
due to mutations in the Ataxia-Telangiectasia Mutated (ATM) gene. It is believed that there is …

[PDF][PDF] Opinions of syrian refugee and turkish citizen pregnant women regarding the ministry of health's practices to combating smoking

R Can, S Kurtulus - Medicine, 2022 - researchgate.net
Laws have been enacted by the Ministry of Health to protect health against smoking. We
aimed to contribute to the literature by examining the opinions of the citizens of the Republic …

母亲慢性粒细胞白血病对新生儿的影响

丁晶, 肖一涵, 薛玉娟, 付洁, 刘捷, 秦炯… - 临床儿科 …, 2022 - jcp.xinhuamed.com.cn
目的回顾性分析母亲患慢性粒细胞白血病(CML) 对新生儿的影响. 方法对2010 年1 月至2022
年1 月北京大学人民医院产科收治的41 例患CML 孕妇及其分娩的36 例新生儿和同期年龄匹配 …

[HTML][HTML] The differences of hemogram, myelogram, and driver gene mutations in classic myeloproliferative neoplasms

J Wang, J Zhang, J Huang, Y Mei, Z Hong - Blood Cells, Molecules, and …, 2022 - Elsevier
The aim of this study was to explore and compare routine blood features and pathological
characteristics of bone marrow tissues in essential thrombocythemia (ET), polycythemia vera …

Eosinophilic Myocarditis: When Allergies Attack the Heart!

V Jain, A Bansal, D Aggarwal, M Chetrit… - Cardiology in …, 2022 - journals.lww.com
Eosinophilic myocarditis is a clinical condition whereby myocardial injury is mediated by
eosinophilic infiltration. A number of underlying causes, including reactive, clonal, or …

Juvenile myelomonocytic leukemia in a child: a case report of palliative chemotherapy and literature review applied to limited resources centers

N Yolanda, S Gunawan, MFJ Mantik… - Case Reports in …, 2022 - Wiley Online Library
Juvenile myelomonocytic leukemia (JMML) is a rare hematopoietic malignancy in children,
with an incidence of 1.2 per million children per year. At this moment, we present a case …