Machine learning-based drug discovery success depends on molecular representation. Yet
traditional molecular fingerprints omit both the protein and pointers back to structural …

The nucleocapsid (N) protein is one of the four structural proteins of the SARS-CoV-2 virus
and plays a crucial role in viral genome organization and, hence, replication and …

Large oligomeric enzymes control a myriad of cellular processes, from protein synthesis and
degradation to metabolism. The 0.5 MDa large TET2 aminopeptidase, a prototypical …

This study aimed to investigate if differences in β-casein polymorphic structure would affect
the acid-induced (glucono-δ-lactone) gelation behaviour of corresponding skim milks. Gels …

Many efforts have been recently devoted to the design and investigation of multicomponent
pharmaceutical solids, such as salts and cocrystals. The experimental distinction between …

We employed a reductionist approach in designing the first heterochiral tripeptide that forms
a robust heterogeneous short peptide catalyst similar to the “histidine brace” active site of …

Two-dimensional Ruddlesden–Popper (RP) perovskites are emerging materials offering
great synthetic versatility and remarkable features due to the tunability of their crystal …

Tautomerism is one of the most important forms of isomerism, owing to the facile
interconversion between species and the large differences in chemical properties …

Numerous peptides have been utilized to explore the efficacy of their self-assembly to
produce nanostructures to mimic the self-organization capability of biomolecules in nature …

Abstract BACKGROUND 2′‐Fucosyllactose (2′‐FL) is the most abundant human milk
oligosaccharide (HMO) in human milk and has important physiological functions. The market …