Extracellular vesicles in atherothrombosis: From biomarkers and precision medicine to therapeutic targets

L Badimon, T Padro, G Arderiu, G Vilahur… - Immunological …, 2022 - Wiley Online Library
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of global
mortality. Extracellular vesicles (EVs) are small phospholipid vesicles that convey molecular …

Extracellular vesicles as drivers of immunoinflammation in atherothrombosis

R Suades, MF Greco, T Padró, L Badimon - Cells, 2022 - mdpi.com
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality all
over the world. Extracellular vesicles (EVs), small lipid-bilayer membrane vesicles released …

Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis

M Witkowski, M Witkowski, J Friebel… - Cardiovascular …, 2022 - academic.oup.com
Aims Gut microbiota and their generated metabolites impact the host vascular phenotype.
The metaorganismal metabolite trimethylamine N-oxide (TMAO) is both associated with …

Blood cell-derived microvesicles in hematological diseases and beyond

HT Georgatzakou, SP Fortis, EG Papageorgiou… - Biomolecules, 2022 - mdpi.com
Microvesicles or ectosomes represent a major type of extracellular vesicles that are formed
by outward budding of the plasma membrane. Typically, they are bigger than exosomes but …

Angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism as a conjoint regulator of coagulation, fibrinolytic, and RAAS pathway in infertility and …

S Thakur, V Sharma, D Kaur… - Journal of the Renin …, 2022 - journals.sagepub.com
Despite the increase in assisted reproductive technologies, the high rates of infertility and
pregnancy complications are a major concern to infertility specialists worldwide. Infertility …

Role of neutrophils and NETs in animal models of thrombosis

E Carminita, L Crescence, L Panicot-Dubois… - International Journal of …, 2022 - mdpi.com
Thrombosis is one of the major causes of mortality worldwide. Notably, it is not only
implicated in cardiovascular diseases, such as myocardial infarction (MI), stroke, and …

Role of extracellular vesicles in severe pneumonia and sepsis

W Hwang, M Shimizu, JW Lee - Expert opinion on biological …, 2022 - Taylor & Francis
Introduction Extracellular vesicles (EV) released constitutively or following external stimuli
from structural and immune cells are now recognized as important mediators of cell-to-cell …

Plasma tissue factor coagulation activity in post-acute myocardial infarction patients

XC Lim, SMJM Yatim, SY Chong, X Wang… - Frontiers in …, 2022 - frontiersin.org
Introduction Coagulation is involved in fibroproliferative responses following acute
myocardial infarction (AMI). Left ventricular (LV) remodeling following AMI is closely …

Characterising the role of inflammatory lipids in regulating systemic inflammation in arthritis

D Costa - 2022 - orca.cardiff.ac.uk
Rheumatoid arthritis (RA) is linked to an elevated risk of thrombotic events, however, the
mechanisms behind this are so far unknown. The activity of coagulation factors requires a …

[PDF][PDF] Research Article Antiplatelet Activity of Morus alba Leaves Extract, Mediated via Inhibiting Granule Secretion and Blocking the Phosphorylation of Extracellular …

DS Kim, HD Ji, MH Rhee, YY Sung, WK Yang, SH Kim… - academia.edu
Ethnopharmacological Relevance. Morus alba L. leaves (MAE) have been used in fork
medicine for the treatment of beriberi, edema, diabetes, hypertension, and atherosclerosis …