[HTML][HTML] Novel systemic treatment modalities including immunotherapy and molecular targeted therapy for recurrent and metastatic head and neck squamous cell …

S Ghosh, PA Shah, FM Johnson - International journal of molecular …, 2022 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common cancers
worldwide. More than half of patients with HNSCC eventually experience disease …

[HTML][HTML] Research progress in inducing immunogenic cell death of tumor cells

D Xie, Q Wang, G Wu - Frontiers in immunology, 2022 - frontiersin.org
Immunogenic cell death (ICD) is a regulated cell death (RCD) pathway. In response to
physical and chemical signals, tumor cells activate specific signaling pathways that stimulate …

Treg-dominant tumor microenvironment is responsible for hyperprogressive disease after PD-1 blockade therapy

H Wakiyama, T Kato, A Furusawa, R Okada… - Cancer Immunology …, 2022 - AACR
Abstract Programmed cell death 1 (PD-1) blockade therapy can result in dramatic responses
in some patients with cancer. However, about 15% of patients receiving PD-1 blockade …

[HTML][HTML] Near-infrared photoimmunotherapy for oropharyngeal cancer

D Nishikawa, H Suzuki, S Beppu, H Terada, M Sawabe… - Cancers, 2022 - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) represents a potential novel
treatment modality for a range of cancer types, including head and neck cancers. NIR-PIT is …

[HTML][HTML] Near-infrared photoimmunotherapy: design and potential applications for cancer treatment and beyond

D Wei, J Qi, MR Hamblin, X Wen, X Jiang, H Yang - Theranostics, 2022 - ncbi.nlm.nih.gov
Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed cancer treatment
modality based on a target-specific photosensitizer conjugate (TSPC) composed of an NIR …

[HTML][HTML] Quality-of-life evaluation of patients with unresectable locally advanced or locally recurrent head and neck carcinoma treated with head and neck …

I Okamoto, T Okada, K Tokashiki, K Tsukahara - Cancers, 2022 - mdpi.com
Simple Summary Head and neck photoimmunotherapy (HN-PIT) is a new treatment
developed for local control of head and neck carcinoma. This study assessed the quality of …

Spotlight on photoactivatable liposomes beyond drug delivery: an enabler of multitargeting of molecular pathways

MA Saad, T Hasan - Bioconjugate chemistry, 2022 - ACS Publications
The potential of photoactivating certain molecules, photosensitizers (PS), resulting in
photochemical processes, has long been realized in the form of photodynamic therapy …

[HTML][HTML] Near-infrared photoimmunotherapy (NIR-PIT) in urologic cancers

H Fukushima, B Turkbey, PA Pinto, A Furusawa… - Cancers, 2022 - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) is a novel molecularly-
targeted therapy that induces rapid cancer cell death by systemically administering an …

[HTML][HTML] Disialoganglioside GD2-targeted near-infrared photoimmunotherapy (NIR-PIT) in tumors of neuroectodermal origin

FF Inagaki, T Kato, A Furusawa, R Okada, H Wakiyama… - Pharmaceutics, 2022 - mdpi.com
Disialoganglioside (GD2) is a subtype of glycolipids that is highly expressed in tumors of
neuroectodermal origins, such as neuroblastoma and osteosarcoma. Its limited expression …

[HTML][HTML] An open-source LED array illumination system for automated multiwell plate cell culture photodynamic therapy experiments

K Zhang, S Timilsina, M Waguespack, EM Kercher… - Scientific Reports, 2022 - nature.com
Photodynamic therapy (PDT) research would benefit from an automated, low-cost, and easy-
to-use cell culture light treatment setup capable of illuminating multiple well replicates within …