General anesthetics depress excitatory and/or enhance inhibitory synaptic transmission
principally by modulating the function of glutamatergic or GABAergic synapses, respectively …

Abstract Parvalbumin-expressing (PV+) basket cells are fast-spiking inhibitory interneurons
that exert critical control over local circuit activity and oscillations. PV+ axons are often …

Dravet syndrome is a neurodevelopmental disorder characterized by epilepsy, intellectual
disability, and sudden death due to pathogenic variants in SCN1A with loss of function of the …

Living organisms react to external stimuli to adapt their activity to the environment for
survival. Acquired information is encoded by neurons by action potentials (APs) in a series …

In Alzheimer's disease (AD), a multitude of genetic risk factors and early biomarkers are
known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD …

The majority of autism spectrum disorder (ASD) risk genes are associated with ASD due to
haploinsufficiency, where only one gene copy is functional. Here, using SCN2A …

In the olfactory bulb, mitral cells (MCs) display a spontaneous firing that is characterized by
bursts of action potentials (APs) intermixed with silent periods. Intraburst firing frequency and …

Autism Spectrum Disorder (ASD), Rett syndrome (RTT) and Angelman Syndrome (AS) are
neurodevelopmental disorders (NDDs) that share several clinical characteristics, including …

Inspired by the mechanism of visual attentional selection, a color feature selection unit
consisting of photoreceptors and an attentional selection circuit (ASC) is presented. The …

Unmyelinated fibers in the central nervous system are known to exist in hippocampal mossy
fibers, cerebellar parallel fibers and striatal projection fibers. Previously, we and others …