[HTML][HTML] Dual effect of immune cells within tumour microenvironment: pro-and anti-tumour effects and their triggers

AC Peña-Romero, E Orenes-Piñero - Cancers, 2022 - mdpi.com
Simple Summary The relationship between the immune system and tumours is currently one
of the most studied topics in the field of cancer. Previously, it was thought that a tumour could …

[HTML][HTML] Functional analysis of circulating tumour cells: the KEY to understand the biology of the metastatic cascade

Z Eslami-S, LE Cortes-Hernandez, F Thomas… - British Journal of …, 2022 - nature.com
Metastasis formation is the main cause of cancer-related death in patients with solid
tumours. At the beginning of this process, cancer cells escape from the primary tumour to the …

[HTML][HTML] High throughput, label-free isolation of circulating tumor cell clusters in meshed microwells

M Boya, T Ozkaya-Ahmadov, BE Swain, CH Chu… - Nature …, 2022 - nature.com
Extremely rare circulating tumor cell (CTC) clusters are both increasingly appreciated as
highly metastatic precursors and virtually unexplored. Technologies are primarily designed …

[HTML][HTML] Microfluidic-based technologies for CTC isolation: a review of 10 years of intense efforts towards liquid biopsy

L Descamps, D Le Roy, AL Deman - International Journal of Molecular …, 2022 - mdpi.com
The selection of circulating tumor cells (CTCs) directly from blood as a real-time liquid
biopsy has received increasing attention over the past ten years, and further analysis of …

[HTML][HTML] Basic principles and recent advances in magnetic cell separation

M Frenea-Robin, J Marchalot - Magnetochemistry, 2022 - mdpi.com
Magnetic cell separation has become a key methodology for the isolation of target cell
populations from biological suspensions, covering a wide spectrum of applications from …

Liquid biopsy: a distinctive approach to the diagnosis and prognosis of cancer

T Hirahata, R ul Quraish, A Quraish… - Cancer …, 2022 - journals.sagepub.com
Cancer is a leading cause of morbidity and mortality worldwide. Over the past decades, the
concept of precision cancer medicine has emerged as a novel approach in the field of …

Single extracellular vesicle analysis for early cancer detection

S Ferguson, KS Yang, R Weissleder - Trends in molecular medicine, 2022 - cell.com
Extracellular vesicles (EVs) are actively shed into the circulation from both cancer and host
cells. EVs are emerging as one of the diagnostic frontrunners for early cancer detection …

Fluid nanoporous microinterface enables multiscale-enhanced affinity interaction for tumor-derived extracellular vesicle detection

Q Niu, J Gao, K Zhao, X Chen, X Lin… - Proceedings of the …, 2022 - National Acad Sciences
Tumor-derived extracellular vesicles (T-EVs) represent valuable markers for tumor diagnosis
and treatment guidance. However, nanoscale sizes and the low abundance of marker …

Greatly enhanced CTC culture enabled by capturing CTC heterogeneity using a PEGylated PDMS–Titanium–Gold electromicrofluidic device with glutathione …

EA Kwizera, W Ou, S Lee, S Stewart, JG Shamul, J Xu… - ACS …, 2022 - ACS Publications
The circulating tumor cells (CTCs, the root cause of cancer metastasis and poor cancer
prognosis) are very difficult to culture for scale-up in vitro, which has hampered their use in …

[HTML][HTML] Circulating cells with macrophage-like characteristics in cancer: the importance of circulating neoplastic-immune hybrid cells in cancer

TL Sutton, RK Patel, AN Anderson, SG Bowden… - Cancers, 2022 - mdpi.com
Simple Summary In cancer, disseminated neoplastic cells circulating in blood are a source
of tumor DNA, RNA, and protein, which can be harnessed to diagnose, monitor, and better …