Extrinsic and intrinsic factors influencing metabolic memory in type 2 diabetes

S Vasishta, S Umakanth, P Adiga, MB Joshi - Vascular Pharmacology, 2022 - Elsevier
Direct and indirect influence of pathological conditions in Type 2 Diabetes (T2D) on
vasculature manifests in micro and/or macro vascular complications that act as a major …

[HTML][HTML] Nutrient-response pathways in healthspan and lifespan regulation

A Dabrowska, J Kumar, C Rallis - Cells, 2022 - mdpi.com
Cellular, small invertebrate and vertebrate models are a driving force in biogerontology
studies. Using various models, such as yeasts, appropriate tissue culture cells, Drosophila …

KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis

T Guo, X Han, J He, J Feng, J Jing, E Janečková, J Lei… - Elife, 2022 - elifesciences.org
Epigenetic regulation plays extensive roles in diseases and development. Disruption of
epigenetic regulation not only increases the risk of cancer, but can also cause various …

Vitamin-related phenotypic adaptation to exposomal factors: The folate-vitamin D-exposome triad

M Lucock - Molecular Aspects of Medicine, 2022 - Elsevier
The biological role of two key vitamins, folic acid and vitamin D is so fundamental to life
processes, it follows that their UV sensitivity, dietary abundance (both key exposomal …

[HTML][HTML] Folic acid supplementation modulates offspring genes involved in energy metabolism: In vivo study

BMF de Paula, MA de Souza Pinhel, CF Nicoletti… - Clinical Nutrition Open …, 2022 - Elsevier
Background & aims Nutritional epigenetics involves essential mechanisms for proper
embryonic development in mammals. Changes in this stage cause various metabolic …

Maternal MTHFR 677C>T, 1298A>C gene polymorphisms and risk of offspring aneuploidy

O Miljanović, S Teofilov, M Anđelić, Z Magić… - Prenatal …, 2022 - Wiley Online Library
Objective The objective was to investigate the association between maternal
methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms, crucial for DNA …

Effect of folic acid supplementation on diminished ovarian reserve: study protocol of a single-centre, open-label, randomised, placebo-controlled clinical trial

K Liao, Y Wang, L Zheng, D Lu, J Wu, B Wu, Z Wu… - BMJ open, 2022 - bmjopen.bmj.com
Introduction The prevalence of diminished ovarian reserve (DOR), a common
gynaecological disorder, is approximately 10% across the world. Failure in early diagnosis …

[HTML][HTML] Protocol: Effect of folic acid supplementation on diminished ovarian reserve: study protocol of a single-centre, open-label, randomised, placebo-controlled …

K Liao, Y Wang, L Zheng, D Lu, J Wu, B Wu, Z Wu… - BMJ Open, 2022 - ncbi.nlm.nih.gov
Introduction The prevalence of diminished ovarian reserve (DOR), a common
gynaecological disorder, is approximately 10% across the world. Failure in early diagnosis …

Nutrigenomics of Aging

NM Palminha, SA Hashish, E Rabie… - Nutrigenomics and the …, 2022 - Springer
Aging is the progressive tissue dysfunction ultimately causing deterioration of
organs/systems (Niccoli and Partridge 2012). Many diseases have been linked to aging, for …

Nutritional Epigenomics and Disease Prevention

JB Adetunji, CO Adetunji, S Islam, D Thangadurai - Nutriomics, 2022 - taylorfrancis.com
Diet-gene interaction has been identified to play a crucial role in health maintenance, which
could curtail processes that could lead to disease development or progression. Moreover …