[HTML][HTML] Synapsin III regulates dopaminergic neuron development in vertebrates

G Faustini, F Longhena, A Muscò, F Bono, E Parrella… - Cells, 2022 - mdpi.com
Attention deficit and hyperactivity disorder (ADHD) is a neurodevelopmental disorder
characterized by alterations in the mesocorticolimbic and nigrostriatal dopaminergic …

[HTML][HTML] CRISPR-mediated activation of αv integrin subtypes promotes neuronal differentiation of neuroblastoma neuro2a cells

S Riccardi, LA Cingolani, F Jaudon - Frontiers in Genome Editing, 2022 - frontiersin.org
Neuronal differentiation is a complex process whose dysfunction can lead to brain disorders.
The development of new tools to target specific steps in the neuronal differentiation process …

Dendritic polyglycerol amine: an enhanced substrate to support long-term neural cell culture

JP Clément, L Al-Alwan, SD Glasgow, A Stolow… - Asn …, 2022 - journals.sagepub.com
Long-term stable cell culture is a critical tool to better understand cell function. Most
adherent cell culture models require a polymer substrate coating of poly-lysine or poly …

Spontaneous Ca2+ events are linked to the development of neuronal firing during maturation in mice primary hippocampal culture cells

RA Sokolov, IV Mukhina - Archives of Biochemistry and Biophysics, 2022 - Elsevier
Calcium is one of the most vital intracellular secondary messengers that tightly regulates a
variety of cell physiology processes, especially in the brain. Using a fluorescent Ca 2+ …

[HTML][HTML] Coordinated regulation of CB1 cannabinoid receptors and anandamide metabolism stabilizes network activity during homeostatic downscaling

M Ye, SK Monroe, SM Gay, ML Armstrong… - eneuro, 2022 - eneuro.org
Neurons express overlapping homeostatic mechanisms to regulate synaptic function and
network properties in response to perturbations of neuronal activity. Endocannabinoids …

[HTML][HTML] Simiate and the focal adhesion kinase FAK1 cooperate in the regulation of dendritogenesis

R Rama, K Derlig, N Vießmann, R Gossmann… - Scientific Reports, 2022 - nature.com
Despite the crucial importance of dendritogenesis for the correct functioning of neurons, the
molecular mechanisms underlying neuronal arborisation are still not well understood …

[PDF][PDF] The Effects of Secreted Amyloid Precursor Protein-Alpha on Rodent Astrocytes and Directly Reprogrammed Human Induced Neuron-Like Cells

AJ Chu - 2022 - ourarchive.otago.ac.nz
Alzheimer's disease (AD) is a progressive neurodegenerative disorder. The hallmark
pathological features of AD are intraneuronal aggregates of hyper-phosphorylated tau …