Excising epileptic foci (EF) is the most efficient approach for treating drug‐resistant epilepsy
(DRE). However, owing to the vast heterogeneity of epilepsies, EF in one‐third of patients …

Available online The abnormal carboxylesterase (CES) expression is closely related to
many diseases such as hyperlipidemia, atherosclerosis, obesity, liver cancer, type 2 …

Based on OR logic gate, we proposed a smart near-infrared (NIR) fluorescent probe, named
VPCPP, for simultaneously monitoring local microviscosity, micropolarity, and …

Nitroreductase (NTR), one of the flavin-dependent enzymes and an upregulated enzyme
under tumor hypoxia, has been studied for decades. Many fluorescent probes were …

Carboxylesterase 2 (CES2) has crucial roles in both xenobiotic metabolism and formation of
pathogenic states including cancer. Thus, it is highly critical to monitor intracellular CES2 …

Abstract Carboxylesterase 2 (CES2) is a serine-type hydrolase that plays important roles in
xenobiotic detoxification and lipid metabolism. Its abnormal expression is highly associated …

Accurate detection of carboxylesterases (CEs) plays a crucial role in various disease
physiological processes and ester-containing drug metabolism. However, the reported near …

Herein, an isophorone-derived fluorescent probe, ARP, was developed to realize the
imaging of in vivo hypoxia under the catalysis of the typical enzyme AzoR. Under the …

Activity-based theranostic photosensitizers are highly attractive in photodynamic therapy as
they offer enhanced therapeutic outcome on cancer cells with an imaging opportunity at the …

NAD (P) H: quinone oxidoreductase 1 (NQO1) is overexpressed in a broad range of human
tumors but remains difficult to study. Herein, we report a novel two-photon fluorescent probe …