Effectiveness of curcumin on outcomes of hospitalized COVID-19 patients: A systematic review of clinical trials

A Vahedian-Azimi, M Abbasifard, F Rahimi-Bashar… - Nutrients, 2022 - mdpi.com
Despite the ongoing vaccination efforts, there is still an urgent need for safe and effective
treatments to help curb the debilitating effects of COVID-19 disease. This systematic review …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

The anti-inflammatory and immunomodulatory activities of natural products to control autoimmune inflammation

KD Moudgil, SH Venkatesha - International Journal of Molecular Sciences, 2022 - mdpi.com
Inflammation is an integral part of autoimmune diseases, which are caused by dysregulation
of the immune system. This dysregulation involves an imbalance between pro-inflammatory …

Natural medicines of targeted rheumatoid arthritis and its action mechanism

X Liu, Z Wang, H Qian, W Tao, Y Zhang, C Hu… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease involving joints, with clinical
manifestations of joint inflammation, bone damage and cartilage destruction, joint …

Curcumin-based nanotechnology approaches and therapeutics in restoration of autoimmune diseases

N Rahiman, YV Markina, P Kesharwani… - Journal of Controlled …, 2022 - Elsevier
Autoimmune diseases usually arise as a result of an aberrant immune system attack on
normal tissues of the body, which leads to a cascade of inflammatory reactions. The immune …

[HTML][HTML] Therapeutic potency of curcumin for allergic diseases: A focus on immunomodulatory actions

SM Haftcheshmeh, SR Mirhafez, M Abedi… - Biomedicine & …, 2022 - Elsevier
In light of increasing research evidence on the molecular mechanisms of allergic diseases,
the crucial roles of innate and acquired immunity in the disease's pathogenesis have been …

[HTML][HTML] A bibliometric analysis of the 100 most-cited articles on curcumin

YX Zhou, XY Cao, C Peng - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Extensive studies related to curcumin were carried out over the preceding
several decades. Citation frequencies represent the most prominent contributions in a …

Novel isatin-based hybrids as potential anti-rheumatoid arthritis drug candidates: Synthesis and biological evaluation

J Chen, X Lin, J He, J Liu, J He, C Tao, Q Wang - Bioorganic Chemistry, 2022 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease accompanied with serious symptoms,
such as joint destruction and chronic synovitis. Though many anti-RA drugs could improve …

Micellar Curcumin: Pharmacokinetics and Effects on Inflammation Markers and PCSK‐9 Concentrations in Healthy Subjects in a Double‐Blind, Randomized, Active …

J Grafeneder, U Derhaschnig… - Molecular nutrition & …, 2022 - Wiley Online Library
Scope: Preclinical models have demonstrated the anti‐inflammatory and lipid‐lowering
effects of curcumin. Innovative formulations have been developed to overcome the poor …

Roles of curcumin on cognitive impairment induced by a mixture of heavy metals

HD Nguyen, MS Kim - Neurotoxicity Research, 2022 - Springer
We aimed to explore the molecular mechanisms of curcumin's protective action against
heavy metal-related cognitive impairment (CI). In silico analysis, CTD, SwissADME …