[HTML][HTML] Biosynthesis of alkanes/alkenes from fatty acids or derivatives (triacylglycerols or fatty aldehydes)

RRC Monteiro, SSO da Silva, CL Cavalcante Jr… - Biotechnology …, 2022 - Elsevier
This review summarizes the most relevant advances in the biological transformation of fatty
acids (or derivatives) into hydrocarbons to be used as biofuels (biogasoline, green diesel …

Covalently Immobilized 2‐Deoxyribose‐5‐phosphate Aldolase (DERA) for Biocatalysis in Flow: Utilization of the 3‐Hydroxyaldehyde Intermediate in Reaction …

J Hindges née Bramski, J Döbber, MR Hayes… - …, 2022 - Wiley Online Library
C− C bond forming enzymes, such as 2‐deoxyribose‐5‐phosphate aldolase (DERA), are an
important class of enzymes in synthesis. The use of DERA, with its reaction routes to the …

Development of a Universal NADH Detection Assay for High Throughput Enzyme Evolution Using Fluorescence Activated Droplet Sorting

G Kolaitis, A Jain, D Romeis, T Buryska… - …, 2022 - research-collection.ethz.ch
Directed evolution is an enzyme engineering approach based on the generation and
screening of large mutagenesis libraries, with a view to discovering enzymes with improved …

[HTML][HTML] Reactivity of a Recombinant Esterase from Thermus thermophilus HB27 in Aqueous and Organic Media

R González-González, P Fuciños, E Beneventi… - Microorganisms, 2022 - mdpi.com
The thermoalkalophilic membrane-associated esterase E34Tt from Thermus thermophilus
HB27 was cloned and expressed in Kluyveromyces lactis (KLEST-3S esterase). The …

[HTML][HTML] Structure-based design of biocatalytic panels for pharmaceuticals synthesis

Y Yu, AR Casamajo, W Finnigan, C Schnepel, R Barker… - 2022 - europepmc.org
Biocatalysis is emerging as an attractive option for manufacturing pharmaceuticals.
However, the identification of enzymes for target transformations of interest requires major …

Highly enantioselective synthesis of chiral molecules at modified mesoporous metal electrodes

S Butcha - 2022 - theses.hal.science
One of the basic human needs is access to efficient drugs. For pharmaceutical applications,
compounds used as drugs are very often chiral molecules. They have two possible mirror …

Directed evolution: a new powerful tool in drug development

A Baier, R Szyszka - Contemporary Chemical Approaches for Green and …, 2022 - Elsevier
Enzymes or whole microorganisms have been used for millennia in biotechnological
processes. Biocatalysis and biotransformation are cost-effective and environmentally …