Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Mammalian viral suppressors of RNA interference

WX Li, SW Ding - Trends in biochemical sciences, 2022 - cell.com
The antiviral defense directed by the RNAi pathway employs distinct specificity and effector
mechanisms compared with other immune responses. The specificity of antiviral RNAi is …

Discovery of a widespread presence bunyavirus that may have symbiont‐like relationships with different species of aphids

X An, W Zhang, C Ye, G Smagghe, JJ Wang… - Insect …, 2022 - Wiley Online Library
Aphids are important agricultural pests, vectors of many plant viruses and have
sophisticated relationships with symbiotic microorganisms. Abundant asymptomatic RNA …

[HTML][HTML] Suppression of both intra‐and intercellular RNA silencing by the tombusviral P19 protein requires its small RNA binding property

F Brioudes, F Jay, O Voinnet - The New Phytologist, 2022 - ncbi.nlm.nih.gov
In various organisms, RNA silencing is an antiviral defense whereby Dicer-like (DCL)
RNase III proteins process replication-derived double-stranded (ds) RNA into viral small …

Complex small RNA-mediated regulatory networks between viruses/viroids/satellites and host plants

C Wang, F Jiang, S Zhu - Virus Research, 2022 - Elsevier
Host plants deploy the small RNA (sRNA)-directed RNA silencing pathway to resist invasion
by acellular microorganisms (viruses/viroids/satellites), and, in turn, this pathway is exploited …

The NS4A protein of classical swine fever virus suppresses RNA silencing in mammalian cells

Q Qian, R Xu, Y Wang, L Ma - Journal of Virology, 2022 - Am Soc Microbiol
ABSTRACT RNA interference (RNAi) is a significant posttranscriptional gene silencing
mechanism and can function as an antiviral immunity in eukaryotes. However, numerous …

[HTML][HTML] Coordinated action of RTBV and RTSV proteins suppress host RNA silencing machinery

A Anand, M Pinninti, A Tripathi, SK Mangrauthia… - Microorganisms, 2022 - mdpi.com
RNA silencing is as an adaptive immune response in plants that limits the accumulation or
spread of invading viruses. Successful virus infection entails countering the RNA silencing …

RNA Interference to Modify Phenotypes in Agriculturally Important Pest and Beneficial Insects: Useful Examples and Future Challenges

K De Schutter, G Smagghe - Transgenic Insects: Techniques …, 2022 - cabidigitallibrary.org
The discovery of RNAi brought forth a revolution in fundamental and applied research in non-
model insects and enabled the next wave of revolutions through genome editing techniques …