Predictive biomarkers of response to immune checkpoint inhibitors in hepatocellular carcinoma
A Muhammed, A D'Alessio, A Enica… - Expert Review of …, 2022 - Taylor & Francis
Introduction Hepatocellular carcinoma (HCC) is the most common primary liver cancer and
fourth-leading cause of cancer death. While drug discovery to improve disease survival was …
fourth-leading cause of cancer death. While drug discovery to improve disease survival was …
Activated hepatic stellate cells in hepatocellular carcinoma: their role as a potential target for future therapies
E Ali, A Trailin, F Ambrozkiewicz, V Liška… - International Journal of …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is a global healthcare challenge, which affects more than
815,000 new cases every year. Activated hepatic stellate cells (aHSCs) remain the principal …
815,000 new cases every year. Activated hepatic stellate cells (aHSCs) remain the principal …
Targeting anillin inhibits tumorigenesis and tumor growth in hepatocellular carcinoma via impairing cytokinesis fidelity
J Chen, Z Li, X Jia, W Song, H Wu, H Zhu, Z Xuan, Y Du… - Oncogene, 2022 - nature.com
Targeting cytokinesis can suppress tumor growth by blocking cell division and promoting
apoptosis. We aimed to characterize key cytokinesis regulator in hepatocellular carcinoma …
apoptosis. We aimed to characterize key cytokinesis regulator in hepatocellular carcinoma …
LncRNA THEMIS2‐211, a tumor‐originated circulating exosomal biomarker, promotes the growth and metastasis of hepatocellular carcinoma by functioning as a …
J Yao, X Hua, J Shi, X Hu, K Lui, K He, J Mai… - The FASEB …, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a major challenge for human health. Finding reliable
diagnostic biomarkers and therapeutic targets for HCC is highly desired in the clinic …
diagnostic biomarkers and therapeutic targets for HCC is highly desired in the clinic …
Risk factors and predictive nomograms for early death of patients with advanced hepatocellular carcinoma: a large retrospective study based on the SEER database
H Zhang, X Du, H Dong, W Xu, P Zhou, S Liu… - BMC …, 2022 - Springer
Background Hepatocellular carcinoma (HCC) is a kind of tumor with high invasiveness, and
patients with advanced HCC have a higher risk of early death. The aim of the present study …
patients with advanced HCC have a higher risk of early death. The aim of the present study …
Long noncoding RNA LINC01419 promotes hepatocellular carcinoma malignancy by mediating miR‐485‐5p/LSM4 axis
ZP Sun, ZG Tan, C Peng - The Kaohsiung Journal of Medical …, 2022 - Wiley Online Library
To investigate the effect of long noncoding RNA (LINC01419)/miR‐485‐5p/LSM4 on the
malignant behavior of hepatocellular carcinoma (HCC) cells. The expressions of …
malignant behavior of hepatocellular carcinoma (HCC) cells. The expressions of …
Omega-3 polyunsaturated fatty acids provoke apoptosis in hepatocellular carcinoma through knocking down the STAT3 activated signaling pathway: in vivo and in …
Hepatocellular carcinoma (HCC) is a common type of liver cancer and is a leading cause of
death worldwide. Signal transducer and activator of transcription 3 (STAT3) is involved in …
death worldwide. Signal transducer and activator of transcription 3 (STAT3) is involved in …
PCSK9 suppresses M2-like tumor-associated macrophage polarization by regulating the secretion of OX40L from hepatocellular carcinoma cells
J Hu, M Zhang, L Gui, Q Wan, J Zhong… - Immunological …, 2022 - Taylor & Francis
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) participates in the
development of various cancers, including hepatocellular carcinoma (HCC). Here, we …
development of various cancers, including hepatocellular carcinoma (HCC). Here, we …
A comparison of clinical pathologic characteristics between alpha-fetoprotein negative and positive hepatocellular carcinoma patients from Eastern and Southern …
X Chi, L Jiang, Y Yuan, X Huang, X Yang… - BMC …, 2022 - Springer
Background Alpha-fetoprotein (AFP) is a biomarker used in clinical management of
hepatocellular carcinoma (HCC), however, approximately 40% of HCC patients do not …
hepatocellular carcinoma (HCC), however, approximately 40% of HCC patients do not …
Potential anti-hepatocellular carcinoma properties and mechanisms of action of clerodane diterpenes isolated from Polyalthia longifolia seeds
VB Tatipamula, CV Thonangi, TC Dakal, GS Vedula… - Scientific Reports, 2022 - nature.com
Diterpenes are secondary metabolites that have attracted much attention due to their
potential biological activities including anti-cancer potential. The aim of the current study is …
potential biological activities including anti-cancer potential. The aim of the current study is …