Only a small proportion of patients with cancer show lasting responses to immune
checkpoint blockade (ICB)-based monotherapies. The RNA-editing enzyme ADAR1 is an …

The presence of intratumoral tertiary lymphoid structures (TLS) is associated with positive
clinical outcomes and responses to immunotherapy in cancer. Here, we used spatial …

Gliomas are the most aggressive primary intracranial malignancies with poor overall
survival. ITGA5 is one member of the integrin adhesion molecule family and is implicated in …

Objectives Transcriptomic-based subtyping, consensus molecular subtyping (CMS) and
colorectal cancer intrinsic subtyping (CRIS) identify a patient subpopulation with …

Little is known about the oncogenic role or biological function of copine Ⅷ (CPNE8) in
gastric cancer (GC). Based on TCGA database, we screened for CPNE8 and analyzed the …

Clear cell renal cell carcinoma (ccRCC) is a heterogeneous malignancy with poor
prognosis. Methylation of the N 6 position of adenosine (m 6 A), the most common …

Head and neck squamous cell carcinoma (HNSCC) ranks as the sixth most common cancer
worldwide and has a poor prognosis in the advanced stage. Increasing evidence has shown …

Programmed cell death (PCD) is a process that regulates the homeostasis of cells in the
body, and it plays an important role in tumor immunity. However, the expression profile and …

Disturbances in circadian rhythms are known to affect immune functions. However, the long-
term impact of abnormal circadian rhythms on the immune-related functions of the spleen …

Background: Head and neck squamous cell carcinomas (HNSCCs) are derived from the
mucosal linings of the upper aerodigestive tract, salivary glands, thyroid, oropharynx, larynx …