Oxidative stress in multiple organs after sepsis in elderly rats

W Margotti, MP de Souza Goldim, RS Machado… - Experimental …, 2022 - Elsevier
Aging is a dynamic process, in which morphological and physiological changes occur at all
levels, making the body more vulnerable to acute events. Elderly people are at greater risk …

Neuropeptide W attenuates oxidative multi-organ injury in rats induced with intra-abdominal sepsis

AE Atici, S Arabacı Tamer, HN Levent… - Inflammation, 2022 - Springer
Sepsis leads to systemic hypotension, disturbed perfusion, inflammation, and tissue toxicity
in vital organs. Neuropeptide W (NPW) has modulatory effects in the control of blood …

Effects of medium cutoff membranes on pro-inflammatory cytokine and oxidative marker levels in patients with sepsis who developed acute kidney injury

M Comoglu, F Dede, EC Yenigun, C Topcuoglu… - Blood …, 2022 - karger.com
Introduction: There is insufficient data on the role of the medium cutoff (MCO) membranes in
the clearance of pro-inflammatory cytokines and oxidant radicals in patients with sepsis …

The possible useful effectiveness of sinapic acid sepsis-induced secondary organ damage in rats

A Tanyeli, FNE Akdemir, E Eraslan… - Clinical and …, 2022 - dergipark.org.tr
Objectives: In this study, we investigated the possible useful effectiveness of Sinapic acid on
rat kidney and lung tissues in an experimental cecal ligation puncture (CLP) model …

Comparing the pharmacokinetics and organ/tissue distribution of anti-methicillin-resistant Staphylococcus aureus agents using a rat model of sepsis

S Kobuchi, N Kanda, T Okumi, Y Kano, H Tachi, Y Ito… - Xenobiotica, 2022 - Taylor & Francis
Sepsis is a major cause of death, and sepsis-derived physiological changes complicate the
understanding of drug distribution in organs/tissues, which determines the efficacy and …

The cardioprotective effects of perindopril in a model of polymicrobial sepsis: The role of radical oxygen species and the inflammation pathway

A Topçu, U Kostakoglu, T Mercantepe… - … of Biochemical and …, 2022 - Wiley Online Library
Mortality rates associated with myocardial dysfunction due to sepsis and septic shock are
generally high across the world. The present study focused on the antioxidant and anti …

Effects of Adenosine N1-Oxide and Pioglitazone on Inflammatory and Antioxidant State in Sepsis Caused by Experimental Cecal Puncture in Rat

S Kazemi-Darabadi, S Ahmadiafshar - papers.ssrn.com
Sepsis is an acute condition caused by the systemic inflammatory response syndrome to an
infection that is exacerbated by organs dysfunction. The multi-organ insufficiency is a major …