Network for network concept offers new insights into host-SARS-CoV-2 protein interactions and potential novel targets for developing antiviral drugs

N Eskandarzade, A Ghorbani, S Samarfard… - Computers in biology …, 2022 - Elsevier
Abstract SARS-CoV-2, the causal agent of COVID-19, is primarily a pulmonary virus that can
directly or indirectly infect several organs. Despite many studies carried out during the …

SARS-CoV-2 mutant spectra at different depth levels reveal an overwhelming abundance of low frequency mutations

B Martínez-González, ME Soria, L Vázquez-Sirvent… - Pathogens, 2022 - mdpi.com
Populations of RNA viruses are composed of complex and dynamic mixtures of variant
genomes that are termed mutant spectra or mutant clouds. This applies also to SARS-CoV …

Whole genome sequencing of clinical specimens reveals the genomic diversity of porcine reproductive and respiratory syndrome viruses emerging in China

J Xing, Z Zheng, X Cao, Z Wang, Z Xu… - Transboundary and …, 2022 - Wiley Online Library
The Porcine reproductive and respiratory syndrome virus (PRRSV), a single (+) RNA virus,
is characterized by high genome variability and constant evolution. Owing to increasingly …

[PDF][PDF] Diversity due to mutations in circulating virus strains of SARS-CoV-2 may delay control of COVID-19

SS Patil, C Shivamallu, C Dharmashekara… - JAppl Biol …, 2022 - researchgate.net
Severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) is a beta-coronavirus
(beta-CoV; sarbecovirus), like its predecessors SARS and MERS CoVs. Of the structural …

The value of early positive nucleic acid test and negative conversion time of SARS-CoV-2 RNA in the clinical outcome of COVID-19 patients

X Zang, L Xiong, J Zhu, F Zhao, S Wang, W Zeng… - Frontiers in …, 2022 - frontiersin.org
Background The outbreak of coronavirus disease (COVID-19) poses a great threat to global
public health. At present, the number of newly confirmed COVID-19 cases and deaths is …

Highlight of potential impact of new viral genotypes of SARS-CoV-2 on vaccines and anti-viral therapeutics

A Ghorbani, S Samarfard, M Jajarmi, M Bagheri… - Gene Reports, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of the
coronavirus disease (COVID-19) pandemic, has infected millions of people globally. Genetic …

[图书][B] The quasispecies equation and classical population models

R Cerf, J Dalmau - 2022 - Springer
We are surrounded by a huge heterogeneity of living beings: insects, plants, animals and
humans. Even the creatures belonging to the same species present an extraordinary …