New mass spectrometry imaging (MSI) techniques are gaining importance in various stages
of the drug discovery and development chain as well as in more fundamental studies of drug …

Mass spectrometry imaging (MSI) is emerging as a powerful analytical tool for detection,
quantification, and simultaneous spatial molecular imaging of endogenous and exogenous …

In this study, we examine the suitability of desorption electro-flow focusing ionization (DEFFI)
for mass spectrometry imaging (MSI) of biological tissue. We also compare the performance …

Fixation of samples is broadly used prior to the histological evaluation of tissue samples.
Though recent reports demonstrated the ability to use fixed tissues for mass spectrometry …

The brain is the most advanced organ with various complex structural and functional
microregions. It is often challenging to understand what and where the molecular events …

Mass spectrometry imaging (MSI) encompasses a powerful suit of techniques which provide
spatially resolved atomic and molecular information from almost any sample type. MSI is …

Diazepam (DZP) was routinely prescribed to a large population troubled with anxiety
disorders. However, due to the overuse and misuse, DZP and its chlorination disinfection …

Simvastatin (SV) is a hypolipidemic agent, and it is the 2nd most widely prescribed lipid-
lowering drug. Here, the detection and characterization of SV and its metabolites was …

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for
absolute quantification of drugs in pharmacokinetic (PK) studies. However, all spatial …