Functional roles of lncRNA-TUG1 in hepatocellular carcinoma

M Farzaneh, M Ghasemian, F Ghaedrahmati… - Life Sciences, 2022 - Elsevier
Hepatocellular carcinoma (HCC) or hepatoma is malignant cancer that starts from the main
liver cells. Although various classical methods have been used for patients with HCC …

The various regulatory functions of long noncoding RNAs in apoptosis, cell cycle, and cellular senescence

M Heydarnezhad Asl… - Journal of cellular …, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a group of noncoding cellular RNAs involved in
significant biological phenomena such as differentiation, cell development, genomic …

[HTML][HTML] Exosomal lncRNA TUG1 from cancer-associated fibroblasts promotes liver cancer cell migration, invasion, and glycolysis by regulating the miR-524-5p/SIX1 …

L Lu, J Huang, J Mo, X Da, Q Li, M Fan, H Lu - Cellular & Molecular Biology …, 2022 - Springer
Background Increasing evidence suggests that taurine upregulated gene 1 (TUG1) is crucial
for tumor progression; however, its role in hepatocellular carcinoma (HCC) and the …

[HTML][HTML] Interplay of LncRNAs NEAT1 and TUG1 in incidence of cytokine storm in appraisal of COVID-19 infection

SI Tayel, EA El-Masry, GA Abdelaal… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Background: In 2019, the coronavirus pandemic emerged, resulting in the highest mortality
and morbidity rate globally. It has a prevailing transmission rate and continues to be a global …

[HTML][HTML] The regulatory functions and the mechanisms of long non-coding RNAs in cervical cancer

Q Yang, A Al-Hendy - Cells, 2022 - mdpi.com
Cervical cancer is one of the leading causes of death in gynecology cancer worldwide. High-
risk human papillomaviruses (HPVs) are the major etiological agents for cervical cancer …

[HTML][HTML] The roles of long non-coding RNAs in lung cancer

Z Cao, L Oyang, X Luo, L Xia, J Hu, J Lin, S Tan… - Journal of …, 2022 - ncbi.nlm.nih.gov
Lung cancer is the most common malignancy, being a serious threat of human lives. The
incidence and mortality of lung cancer has been increasing rapidly in the past decades …

GAE-LGA: integration of multi-omics data with graph autoencoders to identify lncRNA–PCG associations

M Gao, S Liu, Y Qi, X Guo, X Shang - Briefings in Bioinformatics, 2022 - academic.oup.com
Long non-coding RNAs (lncRNAs) can disrupt the biological functions of protein-coding
genes (PCGs) to cause cancer. However, the relationship between lncRNAs and PCGs …

[HTML][HTML] Influence of long non-coding RNA in the regulation of cancer stem cell signaling pathways

K Sonawala, S Ramalingam, I Sellamuthu - Cells, 2022 - mdpi.com
Over the past two decades, cancer stem cells (CSCs) have emerged as an immensely
studied and experimental topic, however a wide range of questions concerning the topic still …

Optimized thyroid transcription factor-1 core promoter-driven microRNA-7 expression effectively inhibits the growth of human non-small-cell lung cancer cells

S Chen, L Guan, X Zhao, J Yang, L Chen… - Journal of Zhejiang …, 2022 - Springer
Targeted gene therapy has become a promising approach for lung cancer treatment. In our
previous work, we reported that the targeted expression of microRNA-7 (miR-7) operated by …

P53 and taurine upregulated gene 1 promotes the repair of the DeoxyriboNucleic Acid damage induced by bupivacaine in murine primary sensory neurons

L Lai, Y Wang, S Peng, W Guo, F Li, S Xu - Bioengineered, 2022 - Taylor & Francis
The research aimed to explore the biological role of p53 protein and long non-coding RNA
(lncRNA) taurine upregulated gene 1 (TUG1) in bupivacaine (bup)-induced neurotoxicity …