Natural products as anticancer agents: current status and future perspectives

A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care

A Mazurakova, L Koklesova, M Samec, E Kudela… - EPMA Journal, 2022 - Springer
Breast cancer incidence is actually the highest one among all cancers. Overall breast cancer
management is associated with challenges considering risk assessment and predictive …

Genesis and mechanism of some cancer types and an overview on the role of diet and nutrition in cancer prevention

N Kamal, MA Ilowefah, AR Hilles, NA Anua, T Awin… - Molecules, 2022 - mdpi.com
Cancer is a major disease with a high mortality rate worldwide. In many countries, cancer is
considered to be the second most common cause of death after cardiovascular disease. The …

Alpinetin: a review of its pharmacology and pharmacokinetics

G Zhao, Y Tong, F Luan, W Zhu, C Zhan… - Frontiers in …, 2022 - frontiersin.org
Flavonoids isolated from medicinal herbs have been utilized as valuable health-care agents
due to their virous biological applications. Alpinetin is a natural flavonoid that emerges in …

Nobiletin as an inducer of programmed cell death in cancer: a review

J Huang, Z Chang, Q Lu, X Chen, M Najafi - Apoptosis, 2022 - Springer
Cancer resistance to therapy is a big issue in cancer therapy. Tumours may develop some
mechanisms to reduce the induction of cell death, thus stimulating tumour growth. Cancer …

Anti-prostate cancer protection and therapy in the framework of predictive, preventive and personalised medicine—comprehensive effects of phytochemicals in …

A Mazurakova, M Samec, L Koklesova, K Biringer… - EPMA Journal, 2022 - Springer
According to the GLOBOCAN 2020, prostate cancer (PCa) is the most often diagnosed male
cancer in 112 countries and the leading cancer-related death in 48 countries. Moreover …

Prostate cancer treatment costs increase more rapidly than for any other cancer—how to reverse the trend?

J Ellinger, A Alajati, P Kubatka, FA Giordano, M Ritter… - EPMA Journal, 2022 - Springer
Abstract According to GLOBOCAN, about 1.41 million new prostate cancer (PCa) cases
were registered in the year 2020 globally. The corresponding socio-economic burden is …

Flavones: Six selected flavones and their related signaling pathways that induce apoptosis in cancer

SH Jeong, HH Kim, SE Ha, MY Park… - International Journal of …, 2022 - mdpi.com
Cancer is a horrific disease that, to date, has no cure. It is caused by various factors and
takes many lives. Apoptosis is a programmed cell death mechanism and if it does not …

Flavonoids-based delivery systems towards cancer therapies

M Ferreira, D Costa, Â Sousa - Bioengineering, 2022 - mdpi.com
Cancer is the second leading cause of death worldwide. Cervical cancer, for instance, is
considered a major scourge in low-income countries. Its development is mostly associated …

Flavonoids target human herpesviruses that infect the nervous system: Mechanisms of action and therapeutic insights

M Šudomová, K Berchová-Bímová, A Mazurakova… - Viruses, 2022 - mdpi.com
Human herpesviruses (HHVs) are large DNA viruses with highly infectious characteristics.
HHVs can induce lytic and latent infections in their host, and most of these viruses are …