Reactive oxygen species: Key players in the anticancer effects of apigenin?

OR Oyenihi, AB Oyenihi, TD Alabi… - Journal of Food …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) exhibit a double‐edged sword in cancer—hence their
modulation has been an attractive strategy in cancer prevention and therapy. The …

[HTML][HTML] Upregulation of Nrf2/HO-1 signaling and attenuation of oxidative stress, inflammation, and cell death mediate the protective effect of apigenin against …

W Al-Amarat, MH Abukhalil, RS Alruhaimi, HA Alqhtani… - Metabolites, 2022 - mdpi.com
Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …

[HTML][HTML] Lipid metabolism disorders contribute to hepatotoxicity of ICR mice induced by nitrosamines exposure

H Zhang, L Lu, C Zhao, Q Liu, Q Zhou, Y Zhang… - Environment …, 2022 - Elsevier
Health risks caused by crucial environmental carcinogens N-nitrosamines triggered
ubiquitous attention. As the liver exerted vital function through metabolic process, lipid …

A review of potential hepatoprotective compounds from medicinal plants

S Nagarajan - Pharmacophore, 2022 - pharmacophorejournal.com
The extraction of pharmaceuticals from their natural sources has been an essential
component of the drug discovery process. In general," drugs" derived from natural sources …

[PDF][PDF] Upregulation of Nrf2/HO-1 signaling and attenuation of oxidative stress, inflammation, and cell death mediate the protective effect of apigenin against …

W Al-Amarat, MH Abukhalil, RS Alruhaimi… - DOI: https://doi. org …, 2022 - academia.edu
Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …

Protective effects of apigenin against edifenphos-induced genotoxicity and cytotoxicity in rat hepatocytes

A Ahmad, A Zafar, S Zargar, A Bazgaifan… - Journal of …, 2022 - Taylor & Francis
Edifenphos (EDF) is an organophosphorus pesticide with antifungal and anti-insecticidal
properties. However, EDF accumulates in various agricultural products and causes potential …

[HTML][HTML] Centaurium erythraea methanol extract improves the functionality of diabetic liver and kidney by mitigating hyperglycemia-induced oxidative stress

MM Đorđević, A Tolić, J Rajić, M Mihailović… - Journal of Functional …, 2022 - Elsevier
The use of medicinal herbs can mitigate oxidative stress-induced diabetic complications and
organ failure. This study investigated hepato-and reno-protective effects of methanol extract …

[HTML][HTML] The effectiveness of ursolic acid niosomes with chitosan coating for prevention of liver damage in mice induced by n-nitrosodiethylamine

A Miatmoko, AA Faradisa, AA Jauhari, BS Hariawan… - Scientific Reports, 2022 - nature.com
Ursolic acid (UA) is a pentacyclic triterpene carboxylic acid which produces various effects,
including anti-cancer, hepatoprotective, antioxidant and anti-inflammatory. However, UA …