[HTML][HTML] The gut microbiota in inflammatory bowel disease
P Qiu, T Ishimoto, L Fu, J Zhang, Z Zhang… - Frontiers in cellular and …, 2022 - frontiersin.org
Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is
increasing rapidly with the continuous growth of the economy. A large number of studies …
increasing rapidly with the continuous growth of the economy. A large number of studies …
[HTML][HTML] Microbiota medicine: towards clinical revolution
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …
[HTML][HTML] Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery
J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …
Recent applications of immunomodulatory biomaterials for disease immunotherapy
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease
C Shi, J Dawulieti, F Shi, C Yang, Q Qin, T Shi… - Science …, 2022 - science.org
A therapeutic strategy that targets multiple proinflammatory factors in inflammatory bowel
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …
A valence‐engineered self‐cascading antioxidant nanozyme for the therapy of inflammatory bowel disease
Q Wang, C Cheng, S Zhao, Q Liu, Y Zhang… - Angewandte …, 2022 - Wiley Online Library
Antioxidant treatment strategy by scavenging reactive oxygen species (ROS) is a highly
effective disease treatment option. Nanozymes with multiple antioxidant activities can cope …
effective disease treatment option. Nanozymes with multiple antioxidant activities can cope …
Design of diselenide-bridged hyaluronic acid nano-antioxidant for efficient ROS scavenging to relieve colitis
J Xu, T Chu, T Yu, N Li, C Wang, C Li, Y Zhang… - Acs Nano, 2022 - ACS Publications
Overproduction of reactive oxygen species (ROS), a key characteristic of inflammatory bowel
disease (IBD), is responsible for dysregulation of signal transduction, inflammatory …
disease (IBD), is responsible for dysregulation of signal transduction, inflammatory …
Mesenchymal stem cell‐derived extracellular vesicles with high PD‐L1 expression for autoimmune diseases treatment
Autoimmune diseases are the third most common disease influencing the quality of life of
many patients. Here, a programmed cell death‐ligand 1+(PD‐L1) mesenchymal stem cell …
many patients. Here, a programmed cell death‐ligand 1+(PD‐L1) mesenchymal stem cell …
Physiologically Inspired Mucin Coated Escherichia coli Nissle 1917 Enhances Biotherapy by Regulating the Pathological Microenvironment to Improve Intestinal …
X Yang, J Yang, Z Ye, G Zhang, W Nie, H Cheng… - ACS …, 2022 - ACS Publications
The delivery of probiotics to the microbiota is a promising method to prevent and treat
diseases. However, oral probiotics will suffer from gastrointestinal insults, especially the …
diseases. However, oral probiotics will suffer from gastrointestinal insults, especially the …
A Smart Nanoreactor Based on an O2-Economized Dual Energy Inhibition Strategy Armed with Dual Multi-stimuli-Responsive “Doorkeepers” for Enhanced CDT/PTT …
S Qiu, X Wu, Z Li, X Xu, J Wang, Y Du, W Pan… - ACS …, 2022 - ACS Publications
Activated fibroblast-like synovial (FLS) cells are regarded as an important target for
rheumatoid arthritis (RA) treatment via starvation therapy mediated by glucose oxidase …
rheumatoid arthritis (RA) treatment via starvation therapy mediated by glucose oxidase …