Naturally occurring bicoumarin compound daphnoretin inhibits growth and induces megakaryocytic differentiation in human chronic myeloid leukemia cells

YC Huang, CP Huang, CP Lin, KC Yang, YJ Lei… - Cells, 2022 - mdpi.com
Daphnoretin extracted from the stem and roots of Wikstroemia indica (L.) CA Mey has been
shown to possess antiviral and antitumor activities. Herein, we hypothesized that …

SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice

E Solary, C Willekens, L Laplane, T Dragher… - 2022 - researchsquare.com
Heterozygous mutation targeting proline 95 in Serine/Arginine-rich Splicing Factor 2
(SRSF2), associates with V617F mutation in Janus Activated Kinase 2 (JAK2) in some …