In vivo and in silico monitoring bone regeneration during distraction osteogenesis of the mouse femur

R Fu, D Bertrand, J Wang, K Kavaseri, Y Feng… - Computer Methods and …, 2022 - Elsevier
Background and objective Distraction osteogenesis (DO) is a mechanobiological process of
producing new bone by gradual and controlled distraction of the surgically separated bone …

Validation of the modified radiographic union score for tibia fractures (mRUST) in murine femoral fractures

VJ Alentado, AM Knox, CA Staut, AC McGuire… - Frontiers in …, 2022 - frontiersin.org
Bony union is a primary predictor of outcome after surgical fixation of long bone fractures.
Murine models offer many advantages in assessing bony healing due to their low costs and …

[HTML][HTML] Tissue-level regeneration and remodeling dynamics are driven by mechanical stimuli in the microenvironment in a post-bridging loaded femur defect healing …

GR Paul, P Vallaster, M Rüegg… - Frontiers in Cell and …, 2022 - frontiersin.org
Bone healing and remodelling are mechanically driven processes. While the generalised
response to mechanical stimulation in bone is well understood, much less is known about …

Neuroprotective effect of HOTAIR silencing on isoflurane-induced cognitive dysfunction via sponging microRNA-129-5p and inhibiting neuroinflammation

Y Wang, S Zhao, G Li, D Wang, Y Jin - Neuroimmunomodulation, 2022 - karger.com
Introduction: This article purposed to detect the function of the HOTAIR and
HOTAIR/microRNA-129-5p (miR-129-5p) axis on the isoflurane (ISO)-injured cells and rat …

Epimorphic regeneration of the mouse digit tip is finite

CP Dolan, TJ Yang, K Zimmel, F Imholt… - Stem cell research & …, 2022 - Springer
Background Structural regeneration of amputated appendages by blastema-mediated,
epimorphic regeneration is a process whose mechanisms are beginning to be employed for …

X-ray computed microtomography datasets for osteogenic nanofibrous coated titanium implants

S Das, K Dholam, S Gurav, K Bendale, A Ingle… - Scientific Data, 2022 - nature.com
Surface modifications of titanium implant influences the quality of osseointegration and are
associated with favourable treatment prognosis in orthopaedic and cranio-maxillofacial …