[HTML][HTML] Intracellular mono-ADP-ribosyltransferases at the host–virus interphase
B Lüscher, M Verheirstraeten, S Krieg… - Cellular and Molecular Life …, 2022 - Springer
The innate immune system, the primary defense mechanism of higher organisms against
pathogens including viruses, senses pathogen-associated molecular patterns (PAMPs). In …
pathogens including viruses, senses pathogen-associated molecular patterns (PAMPs). In …
[HTML][HTML] Action and function of helicases on RNA G-quadruplexes
M Caterino, K Paeschke - Methods, 2022 - Elsevier
The nucleic acid structure called G-quadruplex (G4) is currently discussed to function in
nucleic acid-based mechanisms that influence several cellular processes. They can …
nucleic acid-based mechanisms that influence several cellular processes. They can …
[HTML][HTML] Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication
Hepatitis E virus (HEV) infections are a leading cause of acute viral hepatitis in humans and
pose a considerable threat to public health. Current standard of care treatment is limited to …
pose a considerable threat to public health. Current standard of care treatment is limited to …
[HTML][HTML] Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex
Y Feng, S Grotegut, P Jovanovic, V Gandin… - Frontiers in …, 2022 - frontiersin.org
The translation initiation complex 4F (eIF4F) is a rate-limiting factor in protein synthesis.
Alterations in eIF4F activity are linked to several diseases, including cancer and infectious …
Alterations in eIF4F activity are linked to several diseases, including cancer and infectious …
[HTML][HTML] 环状RNA 翻译蛋白在癌症中的研究进展
柯双熬， 赵胜男， 刘玉， 卓情， 童祥文， 徐瑶 - 生物工程学报, 2022 - cjb.ijournals.cn
环状RNA (circular RNA, circRNA) 是一种单链环状闭合RNA 分子, 由线性RNA
通过反向剪接形成, 具有稳定, 高度保守, 组织特异性等特点. circRNA 能够通过形成竞争性内源 …
通过反向剪接形成, 具有稳定, 高度保守, 组织特异性等特点. circRNA 能够通过形成竞争性内源 …